Fig. 2

FOXD2-AS1 knockdown inhibits HA cell growth, migration, and invasion. a qRT-PCR to detect FOXD2-AS1 expression, b CCK-8 assay to detect cell proliferation, c Colony formation to detect colony formation ability, d qRT-PCR to detect PCNA expression, e Wound-healing assay to detect cell migration, f Transwell invasion assay to detect cell invasion, and g qRT-PCR to detect MMP-2, MMP-9, E-Cadherin, and N-Cadherin expression in HA cell with si-FOXD2-AS1 or siR-NC transfection. FOXD2-AS1: FOXD2 adjacent opposite strand RNA 1; HA: hemangioma; qRT-PCR: quantitative reverse-time PCR; CCK-8: cell counting kit-8; siR-NC: negative control small interfering RNA; si-FOXD2-AS1: small interfering RNA against FOXD2-AS1