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Fig. 2 | Cancer Cell International

Fig. 2

From: LncRNA NNT-AS1 contributes to the cisplatin resistance of cervical cancer through NNT-AS1/miR-186/HMGB1 axis

Fig. 2

Knockdown of NNT-AS1 inhibits DDP-resistant CC cells viability and proliferation but induces apoptosis. a The expression of NNT-AS1 was measured in HeLa/DDP and SiHa/DDP cells after transfection with sh-NNT-AS1. b–e Cell viability and proliferation of HeLa/DDP and SiHa/DDP cells were detected by MTT assay. f The apoptosis rates were analyzed by Flow Cytometry in HeLa/DDP and SiHa/DDP cells. g, h The protein expression of cleaved caspase-3, Bcl-2 and Bax in HeLa/DDP and SiHa/DDP cells was detected by western blot. *P < 0.05

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