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Fig. 2 | Cancer Cell International

Fig. 2

From: Nicotinamide N-methyltransferase inhibits autophagy induced by oxidative stress through suppressing the AMPK pathway in breast cancer cells

Fig. 2

NNMT inhibited autophagy induced by H2O2. a, c The autophagosomes in the two cell models after H2O2 treatment were imaged by transmission electron microscopy. A representative result from three independent experiments. b, d The quantification results of (a) and (c), respectively (**p < 0.01 and ***p < 0.001). e, g The LC3B protein level in the two cell models after H2O2 treatment was determined by Western blotting. A representative result from three independent experiments. f, h The quantification results of (e) and (g), respectively. The protein levels were normalized to β-actin (**p < 0.01 and ***p < 0.001)

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