Fig. 4

NNMT decreased the inhibition of cell viability and ATP production and the induction of ROS production induced by H₂O₂. a, c, e The cell viability, intracellular ROS and ATP levels in the SK-BR-3 cell model after H₂O₂ treatment were assessed. The data were normalized to the group of SK-BR-3-Vector without H₂O₂ treatment, which was defined as 1. b, d, f The cell viability, intracellular ROS and ATP level in the MDA-MB-231 cell model after H₂O₂ treatment was assessed. The data were normalized to those of the MDA-MB-231-NC group without H₂O₂ treatment, which was defined as 1 (*p < 0.05, **p < 0.01 and ***p < 0.001)