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Fig. 5 | Cancer Cell International

Fig. 5

From: Nicotinamide N-methyltransferase inhibits autophagy induced by oxidative stress through suppressing the AMPK pathway in breast cancer cells

Fig. 5

NNMT inhibited H2O2-induced autophagy by suppressing the AMPK-ULK1 pathway. a, c The p-AMPK, p-ULK1, AMPK, ULK1 and LC3B protein levels in the two cell models after H2O2 treatment were determined by Western blotting. A representative result from three independent experiments. b, d The quantification results of (a) and (c), respectively. The protein levels were normalized to β-actin (**p < 0.01 and ***p < 0.001)

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