Table 2 The potential targets and function of the lncRNAs included in our study
From: Long noncoding RNAs as potential biomarkers in retinoblastoma: a systematic review and meta-analysis
First author | LncRNA type | Expression | Potential target(s) | Pathways |
|---|---|---|---|---|
Xuezhi Wu | PVT1 | Upregulated | miR-488-3p | ↑ Cancer progression; ↓ cell apoptosis; ↓ G1/S arrest; ↑ Migration and invasion |
Fengqin Hao | AFAP1-AS1 | Upregulated | NA | ↑ Cell proliferation; ↑ cell cycle progression; ↑ cell migration and invasion |
Ge Yang | HOTAIR | Upregulated | miR‐613 | ↓ Cell apoptosis; ↑ Cell proliferation and cell viability |
Shizheng Su | BANCR | Upregulated | NA | ↑ Cell proliferation, migration and invasion; ↑ Retinoblastoma progression |
Li Li | H19 | Upregulated | NA | ↑ Cell proliferation, apoptosis; migration and invasion; ↑ Retinoblastoma progression |
Jingxian Wang | DANCR | Upregulated | miR-34c; miR-613 | ↑ Proliferation, migration, invasion, and epithelial-mesenchymal transition (EMT); ↑ tumor growth |
Guigang Yan | LINC00202 | Upregulated | miR-3619-5p | ↑ Cell proliferation, migration and invasion |
L.-L. Bi | MT1JP | Downregulated | Wnt/β-Catenin | ↑ G0/G1; ↑ cell apoptosis; ↓ Cell proliferation, migration and invasion |
Weiwei Shang | BDNF-AS | Downregulaed | NA | ↓ Cancer proliferation and migration; ↑ Cell-cycle arrest |