Fig. 3

Identification of consensus clusters by m6A regulators. a The consensus map of NMF clustering results in the total TCGA cohort. Patients were divided into cluster 1 and cluster 2 according to the expression profiles of 19 m6A regulators. b The relationship between cophenetic, dispersion, evar, residuals, rss and silhouette coefficients with respect to number of clusters. c, d The survival curve of DFS (P = 0.034) and OS (P = 0.056) in cluster 1 and cluster 2. e The correlation analysis of m6A methylation regulators and clinical phenotypes in cluster 1 and cluster 2. The result showed that these 2 clusters has statistical differences in extrathyroidal extension, T and N classifications (*P < 0.05, **P < 0.01, ***P < 0.001)