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Fig. 2 | Cancer Cell International

Fig. 2

From: Circular RNA circ-CSPP1 regulates CCNE2 to facilitate hepatocellular carcinoma cell growth via sponging miR-577

Fig. 2

Circ-CSPP1 promoted proliferation and inhibits apoptosis of NSCLC cells. a The schematic illustration of circ-CSPP1 expression vector and shRNAs. b The transfection efficiency of overexpression of circ-CSPP1 (named as circ-CSPP1) and sh-circ-CSPP1 in Hep3B and SK-HEP-1 cells was analyzed by qRT-PCR. c The effects of overexpression or knockdown of circ-CSPP1 on the mRNA expression of linear CSPP1. d CCK-8 assay was used to determine cell proliferation. e The colony formation assay was performed. (F) The cell apoptosis was determined by flow cytometry. g The migratory ability of HCC cells was decreased by wound healing assay. (H) The transwell assay showed the number of invasive cells. *p < 0.05; **p < 0.01 and ***p < 0.001

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