Fig. 3

SNHG16 is a sponge of miR-338-3p. a The putative binding site between SNHG16 and miR-338-3p was predicted. b–e The interaction between SNHG16 and miR-338-3p was confirmed by the dual-luciferase reporter assay and RIP assay in SK-N-AS-R and SK-N-SH-R cells, respectively. f The correlation between SNHG16 and miR-338-3p was analyzed using Spearman’s correlation test. g The relative expression of miR-338-3p in SK-N-AS-R and SK-N-SH-R cells transfected with pcDNA, SNHG16, si-NC, or si-SNHG16 was detected by qRT-PCR (N = 3). N means that triplicate individual experiments were performed, and the average was taken. *P < 0.05