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Table 1 The significant changes of HSP associated genes expression levels between different types of Head and neck cancer and normal tissues (ONCOMINE database)

From: The expression profiles and prognostic values of HSPs family members in Head and neck cancer

Gene

Types of head and neck cancer vs. normal

Fold change

p value

T test

Reference (PMID)

HSPH1

Tongue carcinoma vs. normal

2.902

5.56E−7

6.528

Pyeon, 17510386

Tongue squamous cell carcinoma vs. normal

2.136

7.85E−5

4.433

Ye, 18254958

Head and neck squamous cell carcinoma vs. normal

1.896

1.37E−5

5.107

Ginos, 14729608

Tall cell variant thyroid gland papillary carcinoma vs. normal

1.178

3.22E−6

7.594

Giordano, 16609007

Hypopharyngeal squamous cell carcinoma vs. normal

2.982

0.033

2.362

Schlingemann, 16205657

HSPD1

Salivary gland adenoid cystic carcinoma vs. normal

1.500

3.23E−4

4.102

FriersonHF, 12368205

Head and neck squamous cell carcinoma vs. normal

2.282

4.67E−7

6.773

Ginos, 14729608

Floor of the mouth carcinoma vs. normal

2.488

9.57E−7

7.144

Pyeon, 17510386

Nasopharyngeal carcinoma vs. normal

1.812

3.60E−5

5.246

Sengupta, 16912175

Tongue squamous cell carcinoma vs. normal 

1.732

1.59E−5

4.785

Ye, 18254958

SERPINH1

Head and neck squamous cell carcinoma vs. normal

6.350

1.25E−6

12.064

Cromer, 14676830

Tongue squamous cell carcinoma vs. normal

3.148

1.09E−10

7.757

Estilo,19138406

Salivary gland adenoid cystic carcinoma vs. normal

308.933

3.74E−6

7.691

FriersonHF, 12368205

Oral cavity squamous cell carcinoma vs. normal

2.072

2.44E−9

7.125

Peng,21853135

Tongue squamous cell carcinoma vs. normal

2.022

2.05E−9

7.405

Talbot, 15833835

HSPA4

Thyroid gland oncocytic follicular carcinoma vs. normal

1.259

1.32E−4

6.863

Giordano, 16609007

Oral cavity carcinoma vs. normal

2.732

4.49E−6

6.212

Pyeon, 17510386

Tongue squamous cell carcinoma vs. normal

1.478

1.74E−6

5.146

Talbot, 15833835

Follicular variant thyroid gland papillary carcinoma vs. normal

1.017

4.02E−4

3.464

TCGA, 2013

Oral cavity squamous cell carcinoma epithelia vs. normal

1.199

0.002

3.391

Toruner, 15381369

HSP90AA1

Floor of the mouth carcinoma vs. normal

3.010

1.40E−8

8.051

Pyeon, 17510386

Oral cavity carcinoma vs. normal

3.878

6.57E−9

8.959

Pyeon, 17510386

Tongue carcinoma vs. normal

2.549

2.98E−7

6.220

Pyeon, 17510386

Tonsillar carcinoma vs. normal

2.641

1.81E−6

6.050

Pyeon, 17510386

Hypopharyngeal squamous cell carcinoma vs. normal

2.931

0.011

3.044

Schlingemann, 16205657

  1. TCGA the Cancer Genome Atlas
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Cancer Cell International

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