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Fig. 7 | Cancer Cell International

Fig. 7

From: Downexpression of HSD17B6 correlates with clinical prognosis and tumor immune infiltrates in hepatocellular carcinoma

Fig. 7

Expression of HSD17B6 is negatively regulated by DNA methylation. a Correlation of HSD17B6 expression with methylation status of HSD17B6 promoter in TCGA-LIHC datasets. b, c Effect of 5-aza treatment on the mRNA expression of HSD17B6 in HepG2 cells (b re-analysis of data form GSE5230), and three liver cancer lines (Hep3B, HepG2 and HuH-7) (c re-analysis of data form GSE35313). d Effect of 5-aza treatment on the protein expression of HSD17B6 in HepG2 cell. e–j Correlation of HSD17B6 expression with DNMTs (DNMT1, DNMT3A and DNMT3B) expression in TCGA-LIHC and ICGC-LIRI-JP liver datasets

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