Fig. 1From: Circular RNA and tumor microenvironmentMolecular mechanism of circRNAs. A circRNAs sponge miRNA to release mRNA and regulate transcription indirectly; B circRNAs with RNA-binding protein-binding motifs sponge or decoy RNA binding proteins (RBPs) to regulate transcription; C circRNAs serve as a scaffold for proteins; D circRNAs with internal ribosome entry sites (IRESs) can be translated into peptides or proteins, driven by m6A; E circRNAs regulate transcription of parental genesBack to article page