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Table 2 Details about SNHG6 functioning as ceRNA in tumorigenesis and tumor progression

From: Long noncoding RNA SNHG6 mainly functions as a competing endogenous RNA in human tumors

Cancer type

miRNA

3′–5′ sequence

PBS to SNHG6

Experimental method

Target protein

References

Gastric cancer

miR-101-3p

AAGTCAATAGTGTCATGACAT

12

Luciferase activity assay, RIP, RNA pull down assay

ZEB1

Yan et al. [29]

Breast cancer

miR-26a-5p

TCGGATAGGACCTAATGAACTT

8

Luciferase activity assay

MAPK6

lv et al. [39]

Glioma

miR-101-3p

AAGTCAATAGTGTCATGACAT

12

Luciferase activity assay

NA

Meng et al. [43]

Colorectal cancer

miR-760

AGGGGUGUCUGGGUCUCGGC

7

Dual luciferase reporter assay

FOXC1

Zhu et al. [23]

Hepatocellular carcinoma

miR-26a

CGGATAGGACCTAATGAACTT

8

RIP, luciferase reporter assays.

TAK1

Cao et al. [18]

Hepatocellular carcinoma

miR-26b

TGGATAGGACTTAATGAACTT

8

RIP, luciferase reporter assays.

TAK1

Cao et al. [18]

Lung adenocarcinoma

miR-26a-5p

TCGGATAGGACCTAATGAACTT

8

Luciferase reporter and RNA pull-down assays

E2F7

Liang et al. [37]

Bladder cancer

miR-125b

UCACAAGUCAGGCUCUUGGGAC

8

Luciferase reporter gene assay

Snail1/2 and NUAK1

Wang et al. [42]

Hepatocellular carcinoma

miR-101-3p

AAGTCAATAGTGTCATGACAT

9

Luciferase assay

ZEB1

Chang et al. [9]

Hepatocellular carcinoma

miR-1297

AAGTTCATCATTCCCT

11

Luciferase assay

MAT2A and FUS

Guo et al. [20]

Colorectal cancer

miR-101-3p

NA

NA

qRT-PCR

ZEB1

Wang et al. [26, 42]

Colorectal cancer

miR-214-3p

UGACGGACAGACACGGACGACA

14

Luciferase reporter assay, RNA pull-down assay, ChIP, RIP

EZH2

Xu et al. [24]

Colorectal cancer

miR-26a-5p

CGGATAGGACCTAATGAACTT

8

Luciferase reporter assay, RNA pull-down assay, ChIP, RIP

EZH2

Xu et al. [24]

Colorectal cancer

miR-26b-5p

TGGATAGGACTTAATGAACTT

8

Luciferase reporter assay, RNA pull-down assay, ChIP, RIP

EZH2

Xu et al. [24]

Colorectal cancer

miR-181a-5p

TGAGTGGCTGTCGCAACTTACAA

7

Luciferase reporter assay

E2F5

Yu et al. [25]

Osteocarcinoma

miR-26a-5p

TCGGATAGGACCTAATGAACTT

8

Luciferase reporter assay

ULK1

Zhu et al. [49]

Colorectal cancer

miR-101-3p

AAGTCAATAGTGTCATGACAT

13

Luciferase reporter assay

β-catenin

Shao et al. [12]

Colorectal cancer

miR-26a-5p

CGGATAGGACCTAATGAACTT

8

Dual‑luciferase reporter assay

ULK1

Wang et al. [10]

Hepatocellular carcinoma

miR-139-5p

UGACCUCUGUGCACGUGACAUCU

7

Dual‑luciferase reporter assay,RIP

SERPINH1

Wu et al. [17]

Hepatocellular carcinoma

let-7c-5p

ATGGAG

6

Luciferase reporter assay

c-Myc

Chen et al. [19]

Esophageal squamous cell carcinoma

miR‑186‑5p

UCGGGUUUUCCUCU–UAAGAAAC

13

Luciferase reporter assay, RNA Pull‑Down Assay

HIF1α

Du et al. [33]

Breast cancer

miR-26a-5p

GAUUACUUGAACGAGGCCAC

8

Luciferase assay, RNA Pull‑Down Assay,RIP

VASP

Li et al. [27]

Non-Small Cell Lung Cancer

miR-181d-5p

UGGGUGGCUGUUGUUACUUACAA

10

Dual-Luciferase Reporter Assay, RIP

ETS1

Geng et al. [34]

Non-Small Cell Lung Cancer

miR-944

GAGUAGGCUACAUGUUAUUAAA

13

Dual-Luciferase Reporter Assay, RIP

ETS1

Geng et al. [34]

Non-Small Cell Lung Cancer

miR-490-3p

GUCGUACCUCAGGAGGUCCAAC

7

Luciferase reporter assay

RSF1

Dong et al. [35]

Non-Small Cell Lung Cancer

miR-101-3p

AAGTCAATAGTGTCATGACAT

13

Dual-luciferase reporter assay,RIP

CDYL

Li et al. [36]

  1. PBS predicted binding sites. NA Undetermined, ChIP Chromatin Immunoprecipitation, RIP RNA Immunoprecipitation