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Fig. 5 | Cancer Cell International

Fig. 5

From: The fiber metabolite butyrate reduces gp130 by targeting TRAF5 in colorectal cancer cells

Fig. 5

NaB inhibited activation of the IL-6/JAK2/STAT3 signaling pathway. a–c Western blot analysis of p-JAK2, JAK2, p-STAT3, and STAT3 protein levels in cells treated with NaB (5 mM) for 24 h and IL-6 (25 ng/ml) for 30 min. d Immunostaining for p-STAT3 (red) and DAPI (blue) in cells pretreated with or without NaB (5 mM) for 24 h and IL-6 (25 ng/ml) for 30 min. Scale bar represents 10 μm. (***p < 0.001)

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