Fig. 2

ZKSCAN3 promotes HCC cell migration and invasion in vitro and in vivo. a Hep3B cells that were transfected with corresponding ZKSCAN3 overexpression vectors were subjected to WB for ZKSCAN3. b Cell migration and invasion as measured by Transwell assays were promoted by overexpression of ZKSCAN3 in Hep3B cells. c HCCLM3 cells that were transfected with ZKSCAN3 shRNA and negative control were subjected to WB for ZKSCAN3. d Cell migration and invasion as measured by Transwell assays were inhibited by knockdown of ZKSCAN3 in HCCLM3 cells. e Representative HE staining of lung metastasis of Hep3B or HCCLM3 transfected with respective ZKSCAN3 vector (×100). EV, empty vectors. n = three independent experiments. *P < 0.05