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Table 3 Relationship between SII and clinicopathological variables in breast cancer

From: Prognostic value of the systemic immune-inflammation index in patients with breast cancer: a meta-analysis

Clinicopathological features

No. of studies

No. of patients

OR (95% CI)

p

Effects model

Heterogeneity

I2 (%)

p

LN metastasis (yes vs no)

6

1966

1.38 (1.12–1.69)

0.002

Fixed

44.6

0.108

T stage (T2–T4 vs T1)

5

1805

1.49 (1.17–1.89)

0.001

Fixed

32.7

0.204

TNM stage (II–III vs 0–I)

5

1819

1.37 (1.07–1.77)

0.014

Fixed

0

0.511

Histological grade (G3 vs G1–G2)

4

779

3.71 (1.00–13.73)

0.049

Random

91.2

< 0.001

Pathological type (ILC vs IDC)

3

1443

0.82 (0.55–1.23)

0.345

Fixed

36.4

0.208

Lymphatic invasion (yes vs no)

2

423

1.30 (0.82–2.08)

0.266

Fixed

49.8

0.158

  1. OR odds ratio, G grade, ILC intralobular carcinoma, IDC intraductal carcinoma