Fig. 4
m6A-associated mechanism in melanoma. a Top 10 GO terms for RNA processing. b Network of all genes identified with the a String tool. c Venn diagram of genes identified with different analysis methods to determine the key genes in melanoma. d Network and rank scores of 31 hub genes found in the results from all four methods in (c). e Heat map of genes that had a significant relationship with YTHDF1 or HNRNPA2B1. f Scatter plots of expression of YTHDF1 and HNRNPA2B1 and all genes in (e) and their associations. g Pathway or GO terms of the critical genes in melanoma and their relationship with YTHDF1 or HNRNPA2B1. MCC, maximal clique centrality; MNC, maximum neighborhood component; EPC, edge percolated component. * P < 0.05, δ P < 0.01, Ф P < 0.001, Δ P < 0.0001