Increased expression of YTHDF1 and HNRNPA2B1 as potent biomarkers for melanoma: a systematic analysis

Table 4 Evaluation of hub genes

Gene name	MCC	MNC	Degree	EPC
CDK2	8.37 * 10¹³	20	20	22.494
PTTG1	8.37 * 10¹³	19	19	22.596
CCNA2	8.37 * 10¹³	18	18	22.265
CDT1	8.37 * 10¹³	18	18	22.422
PLK1	8.37 * 10¹³	18	18	22.289
CCNB1	8.37 * 10¹³	18	18	22.443
CDC6	8.37 * 10¹³	18	18	22.361
CDK1	8.37 * 10¹³	18	18	22.219
CDC45	8.37 * 10¹³	18	18	22.28
AURKB	8.37 * 10¹³	18	18	22.373
CHEK1	8.37 * 10¹³	18	18	22.259
BIRC5	8.37 * 10¹³	18	18	22.234
TOP2A	8.37 * 10¹³	18	18	22.419
TTK	8.37 * 10¹³	18	18	22.399
RRM2	8.37 * 10¹³	18	18	22.558
EZH2	4.18 * 10¹³	19	19	22.315
ORC1	4.18 * 10¹³	17	17	22.183
FOXM1	4.18 * 10¹³	17	17	22.118
PCNA	4.18 * 10¹³	17	17	22.174
IL6	3.99 * 10⁷	14	14	17.89
IL1B	3.99 * 10⁷	12	12	16.57
STAT1	3.9 * 10⁷	12	12	16.531
IL10	3.99 * 10⁷	11	11	15.753
CXCL8	3.99 * 10⁷	11	11	15.608
CD86	3.99 * 10⁷	11	11	15.382
CXCL10	3.99 * 10⁷	11	11	15.847
IFNG	3.99 * 10⁷	11	11	15.407
ICAM1	3.99 * 10⁷	11	11	15.725
CXCR4	3.99 * 10⁷	11	11	15.385
IL17A	3.99 * 10⁷	11	11	15.498
TLR7	3.99 * 10⁷	11	11	15.623

MCC maximal clique centrality, MNC maximum neighborhood component, EPC edge percolated component

ISSN: 1475-2867