Fig. 6

PD-L1 acted as a molecular target of miR-377-3p. a The combinative sites between miR-377-3p and 3′UTR of PD-L1 were exhibited after the analysis of Starbase 3.0. b Dual-luciferase reporter assay was employed for validating whether miR-377-3p could combine with PD-L1. c The efficiencies of miR-377-3p mimic or inhibitor were evaluated using qRT-PCR. d PD-L1 protein level was analyzed by western blot in A549 and H82 cells transfected with miR-NC, miR-377-3p, anti-NC or anti-miR-377-3p. All experiments were independently performed three times with N value = 3. *P < 0.05