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Table 2 The top 5 KEGG and Reactome pathways related to proteins involved in UBE2I network

From: UBE2I promotes metastasis and correlates with poor prognosis in hepatocellular carcinoma

Pathway-termDescriptionFalse discovery rate
KEGG pathways
 hsa04120Ubiquitin mediated proteolysis5.25e−08
 hsa03013RNA transport6.03e−08
 hsa05418Fluid shear stress and atherosclerosis1.20e−04
 hsa04064NF-kappa B signaling pathway2.20e−03
 hsa04630Jak-STAT signaling pathway5.00e−03
Reactome pathways
 HSA-2990846SUMOylation9.18e−14
 HSA-3108232SUMO E3 ligases SUMOylate target proteins2.99e−10
 HSA-3108214SUMOylation of DNA damage response and repair proteins9.43e−08
 HSA-3065678SUMO is transferred from E1 to E2 (UBE2I, UBC9)3.48e−07
 HSA-4615885SUMOylation of DNA replication proteins6.65e−07