Fig. 6

Rescue experiment. a CCK8 analysis of TRIM2 knockdown treated A549 cells and TRIM2 overexpression treated H322 cells that had been treated with Snail1 knockdown and overexpression treatments. b qRT-PCR analysis of Cyclin D and PCNA expression in TRIM2 knockdown treated A549 cells and TRIM2 overexpression treated H322 cells that had been treated with Snail1 knockdown and overexpression treatments. c, d Migration and invasion analysis of TRIM2 knockdown treated A549 cells and TRIM2 overexpression treated H322 cells that had been treated with Snail1 knockdown and overexpression treatments. e, f cell survival analysis of three chemotherapy drugs in TRIM2 knockdown treated A549 cells and TRIM2 overexpression treated H322 cells that had been treated with Snail1 knockdown and overexpression treatments. g, h Stem cell pellet analysis of the TRIM2 knockdown treated A549 cells and TRIM2 overexpression treated H322 cells that had been treated with Snail1 knockdown and overexpression treatments. i Wesstern blot analysis of stem cell related biomarkers in TRIM2 knockdown treated A549 cells and TRIM2 overexpression treated H322 cells that had been treated with Snail1 knockdown and overexpression treatments. ***P < 0.001