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Fig. 1 | Cancer Cell International

Fig. 1

From: CircHIPK3 promotes proliferation and metastasis and inhibits apoptosis of renal cancer cells by inhibiting MiR-485-3p

Fig. 1

CircHIPK3 was up-regulated in RC tissues and cells, and not sensitive to RNase R. a The expression of circHIPK3 in RC tissues and adjacent tissues were measured by qRT-PCR (n = 48). b The survival curves were showed. c The expression of circHIPK3 in normal renal tubular epithelial cells HK-2 and RC cells (Caki-1, ACHN, 786-O, 769-P, A498) was measured by qRT-PCR. GAPDH was served as an internal reference. d MRNA expressions of circHIPK3 and HIPK3 after RNase R treatment were measured by qRT-PCR. ***p < 0.001 vs Adjacent tissue; ^^p < 0.01, ^^^p < 0.001 vs HK-2; ###p < 0.001 vs Rnase R-. Rnase R: Ribonuclease R; qRT-PCR: Quantitative Real Time-Polymerase Chain Reaction; GAPDH: Glyceraldehyde-3-phosphate dehydrogenase

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