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Fig. 6 | Cancer Cell International

Fig. 6

From: CircHIPK3 promotes proliferation and metastasis and inhibits apoptosis of renal cancer cells by inhibiting MiR-485-3p

Fig. 6

CircHIPK3 partially reversed the effect of miR-485-3p by regulating associated genes to promote apoptosis and inhibit epithelial-mesenchymal transition. a, b The changes of protein expressions of C caspase-3, Bax and Bcl-2 were detected by Western blot. c MRNA expression changes of Bax and Bcl-2 were detected by qRT-PCR. d, e The expression changes of E-Cad, N-Cad, Vimentin protein were detected by Western blot. f MRNA expression changes of E-Cad, N-Cad, and Vimentin were detected by qRT-PCR. *p < 0.05, **p < 0.01, ***p < 0.001 vs NC + MC; ^^p < 0.01, ^^^p < 0.001 vs NC + M. GAPDH was used as an internal reference. C caspase-3: Clever caspase-3; E-Cad: E-Cadherin; N-Cad: N-Cadherin. NC: negative control for circular RNA. MC: mimic control; M: miR-485-3p mimic

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