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Fig. 7 | Cancer Cell International

Fig. 7

From: CircHIPK3 promotes proliferation and metastasis and inhibits apoptosis of renal cancer cells by inhibiting MiR-485-3p

Fig. 7

MiR-485-3p mimic inhibited tumor growth by regulating apoptosis-related genes, while circHIPK3 partially reversed the effect. a Morphology of transplanted tumor. b The weight of the transplanted tumor. cd Changes of protein expressions of C caspase-3, Bax, and Bcl-2 were detected by Western blot. GAPDH was used as an internal reference. e MRNA expression changes of Bax and Bcl-2 were detected by qRT-PCR. GAPDH was used as an internal reference. **p < 0.01, ***p < 0.001 vs NC + MC; ^^p < 0.01, ^^^p < 0.001 vs NC + M. NC: negative control for circular RNA. MC: mimic control; M: miR-485-3p mimic

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