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Table 2 Univariate and Multivariate Analyses of Prognostic Factors for OS and CSS in patients with non-metastatic RCC (n = 646)

From: Preoperative systemic immune-inflammation index predicts prognosis of patients with non-metastatic renal cell carcinoma: a propensity score-matched analysis

 

OS

Multivariate

CSS

Multivariate

Univariate

Univariate

HR (95% CI)

P-value

HR (95% CI)

P-value

HR (95 CI)

P-value

HR (95% CI)

P-value

Age (≥ 55 vs < 55)

2.9 (1.79–4.72)

< 0.001

1.77 (1.07–2.92)

0.025

2.39 (1.44–3.98)

0.001

  

Gender (male vs female)

1.19 (0.76–1.86)

0.437

  

1.28 (0.78–2.09)

0.332

  

Surgical approach (laparoscopic vs open)

0.29 (0.15–0.56)

< 0.001

0.41 (0.21–0.81)

0.009

0.24 (0.11–0.52)

< 0.001

0.36 (0.16–0.79)

0.011

Type of surgery (partial vs radical)

0.17 (0.08–0.37)

< 0.001

0.37 (0.17–0.83)

0.016

0.11 (0.04–0.31)

< 0.001

0.29 (0.1–0.82)

0.019

Histology (non-clear cell vs clear cell)

0.96 (0.53–1.74)

0.896

  

1.08 (0.58–2.01)

0.807

  

T stage (3–4 vs 1–2)

8.9 (5.78–13.7)

< 0.001

3.99 (2.5–6.37)

< 0.001

12.4 (7.77–19.8)

< 0.001

5.25 (3.16–8.7)

< 0.001

Tumor grade (G3–4 vs G1–2)

4.4 (2.69–7.21)

< 0.001

1.83 (1.06–3.14)

0.03

5.83 (3.25–10.5)

< 0.001

2.15 (1.14–4.08)

0.019

Tumor necrosis (yes vs no)

5.29 (3.39–8.26)

< 0.001

2.38 (1.49–3.79)

< 0.001

6.2 (3.85–9.99)

< 0.001

2.65 (1.62–4.36)

< 0.001

Sarcomatoid feature (yes vs no)

10.66 (4.3–26.4)

< 0.001

2.92 (1.14–7.45)

0.025

12.6 (5.06–31.5)

< 0.001

3.72 (1.44–9.6)

0.007

SII (> 529 vs < 529)

4.23 (2.76–6.49)

< 0.001

2.26 (1.44–3.54)

< 0.001

4.38 (2.74–7.01)

< 0.001

2.17 (1.33–3.55)

0.002