Table 3 Univariate and Multivariate Analyses of Prognostic Factors for OS and CSS in patients with non-metastatic RCC after PSM (n = 326)
| Â | OS | Multivariate | CSS | Multivariate | ||||
|---|---|---|---|---|---|---|---|---|
Univariate | Univariate | |||||||
HR (95% CI) | P-value | HR (95% CI) | P-value | HR (95% CI) | P-value | HR (95% CI) | P-value | |
Age (≥ 55 vs < 55) | 2.06 (1.25–3.4) | 0.004 |  |  | 1.74 (1.03–2.94) | 0.038 |  |  |
Gender (male vs female) | 1.16 (0.71–1.89) | 0.550 |  |  | 1.39 (0.81–2.41) | 0.234 |  |  |
Surgical approach (laparoscopic vs open) | 0.31 (0.15–0.65) | 0.002 | 0.42 (0.2–0.87) | 0.021 | 0.22 (0.09–0.55) | 0.001 | 0.32 (0.13–0.8) | 0.015 |
Type of surgery (partial vs radical) | 0.17 (0.06–0.46) | 0.001 | 0.31 (0.11–0.88) | 0.028 | 0.15 (0.05–0.47) | 0.001 |  |  |
Histology (non–clear cell s clear cell) | 0.71 (0.34–1.48) | 0.365 |  |  | 0.86 (0.41–1.8) | 0.682 |  |  |
T stage (3–4 vs 1–2) | 6.4 (4.04–10.14) | < 0.001 | 4.09 (2.49–6.71) | < 0.001 | 8.91 (5.4–14.7) | < 0.001 | 5.39 (3.14–9.25) | < 0.001 |
Tumor grade (G3–4 vs G1–2) | 2.79 (1.64–4.75) | < 0.001 |  |  | 3.81 (2.03–7.14) | < 0.001 |  |  |
Tumor necrosis (yes vs no) | 2.91 (1.83–4.65) | < 0.001 | 2.15 (1.33–3.48) | 0.002 | 3.38 (2.05–5.57) | < 0.001 | 2.45 (1.46–4.09) | 0.001 |
Sarcomatoid feature (yes vs no) | 5.53 (2.01–15.2) | < 0.001 |  |  | 6.55 (2.37–18.1) | < 0.001 | 3.27 (1.14–9.37) | 0.028 |
SII (> 529 vs < 529) | 1.92 (1.19–3.08) | 0.007 | 1.78 (1.1–2.87) | 0.018 | 1.91 (1.14–3.19) | 0.013 | 1.8 (1.07–3.03) | 0.027 |