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Fig. 6 | Cancer Cell International

Fig. 6

From: LncRNA ST8SIA6-AS1 promotes hepatocellular carcinoma cell proliferation and resistance to apoptosis by targeting miR-4656/HDAC11 axis

Fig. 6

HDAC11 was involved in biological function of ST8SIA6-AS1 in HCC. a pcDNA3-HDAC11 increased HDAC11 protein expression in Huh7 cells. b, c Overexpression of HDAC11 slightly increased cell proliferation and attenuated the anti-proliferation effect of ST8SIA6-AS1 siRNA in Huh7 (b) and Hep3B (c) cells. d, e Overexpression of HDAC11 did not affect cell apoptosis but attenuated the pro-apoptotic effect of ST8SIA6-AS1 siRNA in Huh7 (d) and Hep3B (e) cells. ***vs. control siRNA + pcDNA3, p < 0.001; ## vs. ST8SIA6-AS1 siRNA + pcDNA3, p < 0.01; ### vs. ST8SIA6-AS1 siRNA + pcDNA3, p < 0.001; && vs. control siRNA + pcDNA3, p < 0.01; &&& vs. control siRNA + pcDNA3, p < 0.001

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