Fig. 2

Functional enrichment analysis of methylation‑driven genes in pRCC. a The circle indicates the correlation between the top 11 methylation‑driven genes and their gene ontology terms. b The outer circle represents the expression (logFC) of methylation‑driven genes in each enriched GO (gene ontology) term: red dots on each GO term indicate upregulated methylation‑driven genes and blue dots indicate downregulated methylation‑driven genes. The inner circle indicates the significance of GO terms (log10‑adjusted P values)