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Fig. 4 | Cancer Cell International

Fig. 4

From: LncRNA LINC00261 overexpression suppresses the growth and metastasis of lung cancer via regulating miR-1269a/FOXO1 axis

Fig. 4

LINC00261 overexpression inhibited the migration, invasion and related protein expressions in LC cells. ac The migration of A549 and SPC-A1 cells was determined by wound-healing assay a. Magnification: 100×. The migration of A549 and SPC-A1 cells was calculated (b, c). df The invasion of A549 and SPC-A1 cells was calculated (d, e). The invaded cells (f) were subjected to transwell assay and observed under a microscope (Magnification: 200x). gj The expression levels of MMP-3 and MMP-9 were determined by Western blot. GAPDH served as an internal control. **P < 0.001 vs. blank, ##P < 0.001 vs NC. Blank: cells treated with transfection regent only. NC: pCDH-CMV empty plasmid. LINC00261: pCDH-CMV-LINC00261 overexpression plasmid. All experiments repeated independently in triplicate

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