Fig. 7

The expression levels and correlation analysis of miR-1269a and FOXO1 in LC tissues and cells. a, b The expression levels of miR-1269a and FOXO1 in A549 (a) and SPC-A1 (b) cells measured by qRT-PCR. ^**P < 0.001 vs. blank, ^#P < 0.05, ^##P < 0.001vs NC. c, d The expression levels of miR-1269a (c) and FOXO1 (d) in LC tissues (LC, n = 78) and adjacent normal lung tissues (normal, n = 78) determined by qRT-PCR. ^**P < 0.001 vs. normal.e–g Spearman correlation analysis was performed on LINC00261 and miR-1269a (E, n = 78, r = − 0.595, P < 0.001), FOXO1 and miR-1269a (F, n = 78, r = − 0.558, P < 0.001), LINC00261 and FOXO1 (G, n = 78, r = − 0.442, P < 0.001). Blank: cells treated with transfection regent only. NC, pCDH-CMV empty plasmid. LINC00261, pCDH-CMV-LINC00261 overexpression plasmid. LC, lung cancer. All experiments repeated independently in triplicate