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Fig. 7 | Cancer Cell International

Fig. 7

From: LncRNA LINC00261 overexpression suppresses the growth and metastasis of lung cancer via regulating miR-1269a/FOXO1 axis

Fig. 7

The expression levels and correlation analysis of miR-1269a and FOXO1 in LC tissues and cells. a, b The expression levels of miR-1269a and FOXO1 in A549 (a) and SPC-A1 (b) cells measured by qRT-PCR. **P < 0.001 vs. blank, #P < 0.05, ##P < 0.001vs NC. c, d The expression levels of miR-1269a (c) and FOXO1 (d) in LC tissues (LC, n = 78) and adjacent normal lung tissues (normal, n = 78) determined by qRT-PCR. **P < 0.001 vs. normal.eg Spearman correlation analysis was performed on LINC00261 and miR-1269a (E, n = 78, r = − 0.595, P < 0.001), FOXO1 and miR-1269a (F, n = 78, r = − 0.558, P < 0.001), LINC00261 and FOXO1 (G, n = 78, r = − 0.442, P < 0.001). Blank: cells treated with transfection regent only. NC, pCDH-CMV empty plasmid. LINC00261, pCDH-CMV-LINC00261 overexpression plasmid. LC, lung cancer. All experiments repeated independently in triplicate

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