Fig. 2

Effect of SFRP1 on AR target gene expression. KLK3 (PSA) expression after SFRP1 treatment, ****p ≤ 0.0001, *p ≤ 0.01, (a–c). Effect of exogenous SFRP1 on ERG expression *p ≤ 0.05, **p ≤ 0.005 (d–f). AR localization by Immunofluorescence. Red (DAPI) and green (AR), (g). Expression of AR, **p ≤ 0.01 (h). Cells were treated with DHT and SFRP1 for 24 h (0.01 nM)