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Fig. 1 | Cancer Cell International

Fig. 1

From: TMPO-AS1 promotes cell proliferation of thyroid cancer via sponging miR-498 to modulate TMPO

Fig. 1

The expression of TMPO-AS1 is significantly upregulated in TC tissues and cells and facilitates TC cellular processes. a TMPO-AS1 expression was upregulated in TC tissues from TCGA database. b QRT-PCR assay was utilized to detect the expression of TMPO-AS1 in TC cell lines (A-PTC, CUTC5, TPC-1 and IHH-4) and human normal thyroid epithelial cell line (Nthy-ori3-1). c The knockdown efficiency of TMPO-AS1 was assessed by QRT-PCR assay in TPC-1 and IHH-4 cells transfected with sh-TMPO-AS1#1/2 or sh-NC. d, e The proliferation ability of transfected cells was measured by EdU assays and colony formation assay. f, g TUNEL and cytometry analysis was conducted to evaluate cell apoptosis rate in transfected cells. h, i Migration and invasion were examined in different groups in transwell assays. **p < 0.01

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