Table 3 Genotype and allele distributions of TERT gene rs2853669 and rs2736100 polymorphisms in case and control groups
Genotype/allele | Case n = 102 (%) | Control n = 108 (%) | \( \chi^{2} \) | P | OR (95% CI) |
|---|---|---|---|---|---|
rs2853669 | |||||
AA | 25 (24.51) | 36 (33.33) | – | – | 1 |
AG | 56 (54.90) | 59 (54.63) | 0.954 | 0.329 | 1.367 (0.730–2.561) |
GG | 21 (20.59) | 13 (12.04) | 3.775 | 0.052 | 2.326 (0.985–5.494) |
A | 106 (51.96) | 131 (60.65) | – | – | 1 |
G | 98 (48.04) | 85 (39.35) | 3.220 | 0.073 | 1.425 (0.967–2.099) |
PHWE | 0.133 | ||||
rs2736100 | |||||
AA | 19 (18.63) | 32 (29.63) | – | – | 1 |
AC | 58 (56.86) | 60 (55.56) | 2.032 | 0.154 | 1.628 (0.831–3.190) |
CC | 25 (24.51) | 16 (14.81) | 5.125 | 0.024 | 2.632 (1.129–6.133) |
A | 96 (47.06) | 124 (57.41) | – | – | 1 |
C | 108 (52.94) | 92 (42.59) | 4.504 | 0.034 | 1.516 (1.032–2.229) |
PHWE | 0.157 | ||||