Fig. 3
From: MIAT inhibits proliferation of cervical cancer cells through regulating miR-150-5p
MIAT overexpression inhibited xenograft tumor growth in vivo. a HeLa cells transfected with either E.V or MIAT plasmids were subcutaneously inoculated into immunodeficient nude mice. The xenograft tumors were measured after sacrifice, ***p < 0.001. b Macroscopic images of representative xenograft tumors from both control and MIAT mice at week 5 post-inoculation. c The tumor growth was monitored by digital caliper at day 0, 7, 14, 21, 28 and 35 post-inoculation respectively and the volume was calculated with the formula: volume = (width)2 × length/2. n.s: no significance, ****p < 0.0001. d The persistent overexpression of MIAT in xenograft tumor was validated by real-time PCR. ****p < 0.0001