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Fig. 2 | Cancer Cell International

Fig. 2

From: Antitumor efficacy of cytosine deaminase-armed vaccinia virus plus 5-fluorocytosine in colorectal cancers

Fig. 2

In vitro cytotoxicity effect of vaccinia VG9-CD. Cancer cell lines of HCT 116 (a), CT26.WT (b), MC38 (c), A431 (d), MDA-MB-231 (e), 4T1 (f), SMMC-7721 (g), A549 (h) and normal cells of LO2 (i), NIH3T3 (j) were infected with increasing titers of VG9, VG9-TK- and VG9-CD (MOI = 0, 0.01, 0.1, 1, 2 and 10) for 48 h. 0.1 mg/ml 5-FC was added to cells infected with vaccinia VG9-CD. Cell viability was measured by MTT assay. Each bar represents the mean ± SD (n = 3)

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Cancer Cell International

ISSN: 1475-2867

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