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Fig. 2 | Cancer Cell International

Fig. 2

From: Arsenic trioxide potentiates Gilteritinib-induced apoptosis in FLT3-ITD positive leukemic cells via IRE1a-JNK-mediated endoplasmic reticulum stress

Fig. 2

Gilteritinib synergizes with ATO to reduce proliferation of FLT3-ITD cell lines. a, b MV4-11 and MOLM13 cells treated with Gilteritinib (0–20 nM), ATO (0–4 μM) either alone or in combination for 48 h were detected by CCK8 assay. DMSO treated cells served as a control. c, d Curve of combination index (CI) analyzed by Calcusyn Software was shown. e IC50 was listed according to CCK8 detection

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Cancer Cell International

ISSN: 1475-2867

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