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Table 1 The prognostic significance of ITGA and ITGB superfamily members in predicting RFS in HGSOC patients in TCGA dataset

From: The prognostic value of ITGA and ITGB superfamily members in patients with high grade serous ovarian cancer

VariablesNumber of patientsUnivariate analysisMultivariate analysis
HR (95% CI)P valueHR (95% CI)P value
Age4051.005 (0.993–1.018)0.391//
Stage0.035 0.065
 Early231 1 
 Late3822.255 (1.060–4.796) 2.046 (0.956–4.379) 
Debulking0.546 /
 Optimal3021 //
 Suboptimal1031.100 (0.807–1.501) //
ITGA14050.882 (0.570–1.362)0.570//
ITGA24050.778 (0.528–1.147)0.205//
ITGA44051.060 (0.679–1.655)0.798//
ITGA54051.152(0.950–1.396)0.150//
ITGA64050.863 (0.723–1.029)0.1000.888 (0.739–1.068)0.207
ITGA74051.086 (0.916–1.287)0.341//
ITGA84051.040 (0.714–1.515)0.838//
ITGA94051.054 (0.754–1.451)0.788//
ITGA104050.893 (0.618–1.292)0.549//
ITGB14051.327 (1.002–1.757)0.0481.341 (1.018–1.767)0.037
ITGB24051.039 (0.928–1.162)0.506//
ITGB34050.769 (0.451–1.311)0.335//
ITGB44051.054 (0.936–1.186)0.385//
ITGB54051.080 (0.911–1.280)0.375//
ITGB64050.874 (0.659–1.159)0.349//
ITGB74050.834 (0.614–1.133)0.245//
ITGB84051.124 (0.962–1.314)0.1420.888 (0.739–1.068)0.207