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Table 2 The prognostic significance of ITGA and ITGB superfamily members in predicting OS in HGSOC patients in TCGA dataset

From: The prognostic value of ITGA and ITGB superfamily members in patients with high grade serous ovarian cancer

VariablesNumber of patientsUnivariate analysisMultivariate analysis
HR (95% CI)P valueHR (95% CI)P value
Age4051.025 (1.013–1.038)< 0.0011.023 (1.010–1.036)< 0.001
Stage0.078 0.116
 Early231 1 
 Late3822.079 (0.922–4.685) 1.934 (0.850–4.403) 
Debulking0.017 0.230
 Optimal3021 1 
 Suboptimal1031.430 (1.065–1.920) 1.209 (0.887–1.649) 
ITGA14050.745 (0.474–1.170)0.202//
ITGA24051.037 (0.713–1.508)0.851//
ITGA44051.174 (0.777–1.774)0.446//
ITGA54050.922 (0.759–1.120)0.416//
ITGA64050.976 (0.819–1.163)0.782//
ITGA74050.867 (0.729–1.033)0.1100.849 (0.712–1.013)0.069
ITGA84050.987 (0.682–1.429)0.947//
ITGA94050.944 (0.660–1.348)0.750//
ITGA104051.107 (0.756–1.622)0.601//
ITGB14051.054 (0.832–1.336)0.662//
ITGB24051.004 (0.901–1.118)0.945//
ITGB34050.850 (0.501–1.441)0.546//
ITGB44050.992 (0.881–1.117)0.889//
ITGB54051.087 (0.916–1.290)0.341//
ITGB64050.975 (0.759–1.253)0.844//
ITGB74050.821 (0.592–1.139)0.238//
ITGB84051.207 (1.045–1.394)0.0111.175 (1.014–1.362)0.032