Table 3 Significant changes of TSPANs expression in transcription level between GC and normal gastric tissues (ONCOMINE)
From: Expression and function of transmembrane 4 superfamily proteins in digestive system cancers
Gene | Dataset | Normal (cases) | Tumor (cases) | Fold change | T-test | p-value |
|---|---|---|---|---|---|---|
TSPAN4 | DErrico | Gastric tissue (31) | Gastric mixed adenocarcinoma (4) | 4.346 | 7.553 | 7.17E–9 |
|  |  | Gastric tissue (31) | Diffuse gastric adenocarcinoma (6) | 3.221 | 4.648 | 1.07E–4 |
TSPAN7 | Chen | Gastric tissue (28) | Gastric intestinal type adenocarcinoma (54) | − 2.609 | − 7.307 | 4.42E–10 |
TSPAN9 | Wang | Gastric tissue (15) | Gastric cancer (12) | 2.679 | 3.592 | 7.19E–4 |
TSPAN28 | DErrico | Gastric tissue (31) | Gastric mixed adenocarcinoma (4) | 2.774 | 14.056 | 2.91E–7 |
|  |  | Gastric tissue (31) | Diffuse gastric adenocarcinoma (6) | 2.059 | 5.574 | 5.30E–4 |
|  |  | Gastric tissue (31) | Gastric intestinal type adenocarcinoma (26) | 2.052 | 6.976 | 1.49E–8 |
TSPAN29 | Cho | Gastric tissue (19) | Gastric mixed adenocarcinoma (10) | 3.537 | 6.371 | 1.82E–6 |
|  |  | Gastric tissue (19) | Gastric intestinal type adenocarcinoma (20) | 2.369 | 4.277 | 7.00E–5 |
| Â | Â | Gastric tissue (19) | Gastric adenocarcinoma (4) | 3.077 | 4.303 | 0.004 |
|  |  | Gastric tissue (19) | Diffuse gastric adenocarcinoma (31) | 2.173 | 3.986 | 1.14E–4 |
|  | DErrico | Gastric tissue (31) | Gastric intestinal type adenocarcinoma (26) | 4.263 | 9.674 | 1.14E–13 |
| Â | Â | Gastric Tissue (31) | Diffuse gastric adenocarcinoma (6) | 2.321 | 3.924 | 0.001 |
|  | Wang | Gastric tissue (15) | Gastric cancer (12) | 2.532 | 3.644 | 6.14E–4 |