Table 4 The relationship between ITGA9/LAMB1 expression and clinical parameters of patients with MM
Character | Low ITGA9 group | High ITGA9 group | P-value | Low LAMB1 group | High LAMB1 group | P-value |
|---|---|---|---|---|---|---|
Gender (M/F) | 120/86 | 137/74 | 0.097 | 125/83 | 132/77 | 0.294 |
Age | 57.90 ± 0.66 | 59.37 ± 0.57 | 0.173 | 58.57 ± 0.63 | 58.71 ± 0.61 | 0.913 |
ISS | 0.641 | 0.219 | ||||
I | 87 | 81 | 77 | 91 | ||
II | 63 | 72 | 67 | 68 | ||
III | 62 | 59 | 68 | 53 | ||
R-ISS | 0.896 | 0.001 | ||||
I | 43 | 40 | 30 | 53 | ||
II | 132 | 138 | 141 | 129 | ||
III | 33 | 33 | 38 | 28 | ||
LDH (mean, IU/l) (± SD) | 169.46 ± 6.68 | 156.59 ± 3.24 | 0.628 | 164.98 ± 5.07 | 160.92 ± 5.38 | 0.290 |
β2m (mean, mg/L) (± SD) | 5.220.35 | 4.92 ± 0.29 | 0.966 | 5.36 ± 0.34 | 4.78 ± 0.30 | 0.024 |
BM malignant PCs (mean, %) (± SD) | 16.53 ± 1.15 | 13.85 ± 1.18 | 0.001 | 15.89 ± 1.26 | 14.48 ± 1.06 | 0.824 |
GEP (Standard/High) | 180/33 | 193/20 | 0.039 | 182/31 | 191/22 | 0.120 |