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Fig. 5 | Cancer Cell International

Fig. 5

From: Untargeted LC–MS/MS analysis reveals metabolomics feature of osteosarcoma stem cell response to methotrexate

Fig. 5

Perturbed biological signaling pathways were identified by using KEGG pathway analysis. a Perturbed biological pathways between OS and OSC, b Perturbed biological pathways between OS cells and OS cells after administration of MTX at IC50, c Perturbed biological pathways between OSCs and OSCs after administration of MTX at IC50, d Perturbed biological pathways between OS cells response to MTX and OSCs response to MTX at IC50, respectively. N: differentially expressed metabolites involved in the pathway. Numbers cited in scientific notation in the bracket: statistical P value

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Cancer Cell International

ISSN: 1475-2867

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