Fig. 1

CircDONSON is elevated in DDP-resistant GC tissues and cell lines. a, b qRT-PCR analysis of circDONSON expression in normal gastric mucosa from noncancerous patients and gastric cancer tissues (N = 60), as well as in DDP responsive (N = 35) and non-responsive GC tissues (N = 35). c qRT-PCR analysis of circDONSON expression in gastric epithelial immortalized cell lines GES-1, GC cell lines (AGS and HGC-27), and DDP-resistant GC cell lines (AGS/DDP and HGC-27/DDP). d qRT-PCR analysis of circDONSON and linear DONSON expression in AGS cells treated with actinomycin D (2 μg/mL). e qRT-PCR analysis of circDONSON and linear DONSON expression after treatment with RNase R (10U/3 μg) in AGS cells. n = 3, *P < 0.05