Fig. 2

CircOSBPL10 sponged miR-1179 in CC. a Subcellular fractionation was applied to detect the cellular sublocalization of circOSBPL10 in SiHa and HeLa cells. b MiR-1179, miR-27a-3p and miR-27b-3p were predicted via starBase to have the binding capacity with circOSBPL10. c MiR-1179 expression in CC cell lines and H8 cells was detected via RT-qPCR. d RIP assay unveiled the significant enrichment of circOSBPL10 and miR-1179 in anti-Ago2 group. e Two binding sites between circOSBPL10 and miR-1179 were predicted via starBase. f Luciferase reporter assay validated the interaction between circOSBPL10 and miR-1179. g The expression of circOSBPL10 in SiHa and HeLa cells transfected with pcDNA3.1, pcDNA3.1/circOSBPL10 or pcDNA3.1/circOSBPL10 (mut) was analyzed through RT-qPCR. h, i Cell proliferation and migration in different groups was analyzed via CCK-8 and transwell assays, respectively. *P < 0.05, **P < 0.01