Fig. 1
From: β-catenin promotes MTX resistance of leukemia cells by down-regulating FPGS expression via NF-κB
β-catenin inhibition promoted MTX resistance. a Flow cytometry data analysis of apoptotic cells by Annexin V-APC staining in Jurkat cells. After transfection of RNAi lentivirus, Jurkat cells were treated with 10 μM MTX for 24 h. b The percentage of apoptotic cells significantly increased in the two sh-β-catenin groups, compared with the control group in Jurkat cells. c Flow cytometry data analysis of apoptotic cells by Annexin V-APC staining in MOLT4 cells. After transfection of RNAi lentivirus, MOLT4 cells were treated with 10 μM MTX for 24 h. d The percentage of apoptotic cells significantly increased in the two sh-β-catenin groups, compared with the control group in MOLT4 cells. Columns, mean of 3 individual experiments; Bars, SD;*, p < 0.05, **, p < 0.01, ***, p < 0.001