Fig. 2

Knockdown of MCM3AP-AS1 inhibited the proliferative ability and promoted the apoptosis on LNCaP and PC-3 cells. a, b After knocking down MCM3AP-AS1, the expression of MCM3AP-AS1 in LNCaP (a) and PC-3 (b) cells was detected by qRT-PCR. c, d CCK-8 assay was used to detect the proliferation of LNCaP (c) and PC-3 (d) cells after knocking down MCM3AP-AS1. e EdU assay was used to detected the proliferation of LNCaP and PC-3 cells after knocking down MCM3AP-AS1. f Flow cytometry analysis was used to detect the apoptosis of PCa cells after MCM3AP-AS1 was knocked down. g After knocking down the MCM3AP-AS1, the expressions of Bax and Bcl-2 in LNCaP and PC-3 cells were detected by Western blot. P < 0.05, P < 0.01, and P < 0.001 were denoted by *, **, and *** respectively