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Fig. 5 | Cancer Cell International

Fig. 5

From: MCM3AP-AS1/miR-876-5p/WNT5A axis regulates the proliferation of prostate cancer cells

Fig. 5

Transfection of miR-876-5p mimics inhibited the proliferative ability and promoted the apoptosis on LNCaP and PC-3 cells. a, b qRT-PCR was used to detect the expression level of miR-876-5p in LNCaP (a) and PC-3 (b) cells after the transfection of miR-876-5p mimics. c, d CCK-8 assay was used to detect the proliferation of LNCaP (c) and PC-3 (d) cells transfected with miR-876-5p mimics. e After transfection of miR-876-5p mimics, the proliferation of LNCaP and PC-3 cells was detected by EdU assay. f Flow cytometry analysis was used to detect the apoptosis of PCa cells after the cells were transfected with miR-876-5p mimics. g The expression levels of Bax and Bcl-2 in LNCaP and PC-3 cells were detected by Western blot after transfection of miR-876-5p mimics. P < 0.05, P < 0.01, and P < 0.001 were denoted by *, **, and *** respectively

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