TY - JOUR AU - Bray, F. AU - Ferlay, J. AU - Soerjomataram, I. AU - Siegel, R. L. AU - Torre, L. A. AU - Jemal, A. PY - 2018 DA - 2018// TI - Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries JO - CA Cancer J Clin. VL - 68 UR - https://doi.org/10.3322/caac.21492 DO - 10.3322/caac.21492 ID - Bray2018 ER - TY - JOUR AU - Rahib, L. AU - Smith, B. D. AU - Aizenberg, R. AU - Rosenzweig, A. B. AU - Fleshman, J. M. AU - Matrisian, L. M. PY - 2014 DA - 2014// TI - Projecting cancer incidence and deaths to 2030: the unexpected burden of thyroid, liver, and pancreas cancers in the United States JO - Cancer Res VL - 74 UR - https://doi.org/10.1158/0008-5472.CAN-14-0155 DO - 10.1158/0008-5472.CAN-14-0155 ID - Rahib2014 ER - TY - JOUR AU - Koong, A. C. AU - Mehta, V. K. AU - Le, Q. T. AU - Fisher, G. A. AU - Terris, D. J. AU - Brown, J. M. PY - 2000 DA - 2000// TI - Pancreatic tumors show high levels of hypoxia JO - Int J Radiat Oncol Biol Phys VL - 48 UR - https://doi.org/10.1016/S0360-3016(00)00803-8 DO - 10.1016/S0360-3016(00)00803-8 ID - Koong2000 ER - TY - JOUR AU - Dauer, P. AU - Nomura, A. AU - Saluja, A. AU - Banerjee, S. PY - 2017 DA - 2017// TI - Microenvironment in determining chemo-resistance in pancreatic cancer: neighborhood matters JO - Pancreatology. VL - 17 UR - https://doi.org/10.1016/j.pan.2016.12.010 DO - 10.1016/j.pan.2016.12.010 ID - Dauer2017 ER - TY - JOUR AU - Freedman, S. J. AU - Sun, Z. Y. AU - Poy, F. AU - Kung, A. L. AU - Livingston, D. M. AU - Wagner, G. PY - 2002 DA - 2002// TI - Structural basis for recruitment of CBP/p300 by hypoxia-inducible factor-1 alpha JO - Proc Natl Acad Sci USA VL - 99 UR - https://doi.org/10.1073/pnas.082117899 DO - 10.1073/pnas.082117899 ID - Freedman2002 ER - TY - JOUR AU - Harris, A. L. PY - 2002 DA - 2002// TI - Hypoxia–a key regulatory factor in tumour growth JO - Nat Rev Cancer VL - 2 UR - https://doi.org/10.1038/nrc704 DO - 10.1038/nrc704 ID - Harris2002 ER - TY - JOUR AU - Pereira, T. AU - Zheng, X. AU - Poellinger, L. PY - 2006 DA - 2006// TI - Degradation of the hypoxia-inducible factor 1alpha: where does it happen? JO - Cell Cycle (Georgetown, Tex). VL - 5 UR - https://doi.org/10.4161/cc.5.23.3536 DO - 10.4161/cc.5.23.3536 ID - Pereira2006 ER - TY - JOUR AU - Wu, D. AU - Potluri, N. AU - Lu, J. AU - Kim, Y. AU - Rastinejad, F. PY - 2015 DA - 2015// TI - Structural integration in hypoxia-inducible factors JO - Nature VL - 524 UR - https://doi.org/10.1038/nature14883 DO - 10.1038/nature14883 ID - Wu2015 ER - TY - JOUR AU - Lee, B. L. AU - Kim, W. H. AU - Jung, J. AU - Cho, S. J. AU - Park, J. W. AU - Kim, J. PY - 2008 DA - 2008// TI - A hypoxia-independent up-regulation of hypoxia-inducible factor-1 by AKT contributes to angiogenesis in human gastric cancer JO - Carcinogenesis VL - 29 UR - https://doi.org/10.1093/carcin/bgm232 DO - 10.1093/carcin/bgm232 ID - Lee2008 ER - TY - JOUR AU - Wang, J. AU - Shen, J. AU - Zhao, K. AU - Hu, J. AU - Dong, J. AU - Sun, J. PY - 2019 DA - 2019// TI - STIM1 overexpression in hypoxia microenvironment contributes to pancreatic carcinoma progression JO - Cancer Biol Med. VL - 16 UR - https://doi.org/10.20892/j.issn.2095-3941.2018.0304 DO - 10.20892/j.issn.2095-3941.2018.0304 ID - Wang2019 ER - TY - JOUR AU - Ye, L. Y. AU - Zhang, Q. AU - Bai, X. L. AU - Pankaj, P. AU - Hu, Q. D. AU - Liang, T. B. PY - 2014 DA - 2014// TI - Hypoxia-inducible factor 1α expression and its clinical significance in pancreatic cancer: a meta-analysis JO - Pancreatology. VL - 14 UR - https://doi.org/10.1016/j.pan.2014.06.008 DO - 10.1016/j.pan.2014.06.008 ID - Ye2014 ER - TY - JOUR AU - Shah, S. R. AU - Esni, F. AU - Jakub, A. AU - Paredes, J. AU - Lath, N. AU - Malek, M. PY - 2011 DA - 2011// TI - Embryonic mouse blood flow and oxygen correlate with early pancreatic differentiation JO - Dev Biol. VL - 349 UR - https://doi.org/10.1016/j.ydbio.2010.10.033 DO - 10.1016/j.ydbio.2010.10.033 ID - Shah2011 ER - TY - JOUR AU - Soggia, A. AU - Ramond, C. AU - Akiyama, H. AU - Scharfmann, R. AU - Duvillie, B. PY - 2014 DA - 2014// TI - von Hippel-Lindau gene disruption in mouse pancreatic progenitors and its consequences on endocrine differentiation in vivo: importance of HIF1-α and VEGF-A upregulation JO - Diabetologia VL - 57 UR - https://doi.org/10.1007/s00125-014-3365-y DO - 10.1007/s00125-014-3365-y ID - Soggia2014 ER - TY - JOUR AU - Cheng, K. AU - Ho, K. AU - Stokes, R. AU - Scott, C. AU - Lau, S. M. AU - Hawthorne, W. J. PY - 2010 DA - 2010// TI - Hypoxia-inducible factor-1alpha regulates beta cell function in mouse and human islets JO - J Clin Investig VL - 120 UR - https://doi.org/10.1172/JCI35846 DO - 10.1172/JCI35846 ID - Cheng2010 ER - TY - JOUR AU - Román, C. L. AU - Maiztegui, B. AU - Mencucci, M. V. AU - Ahrtz, L. AU - Algañarás, M. AU - Zotto, H. PY - 2019 DA - 2019// TI - Effects of islet neogenesis associated protein depend on vascular endothelial growth factor gene expression modulated by hypoxia-inducible factor 1-alpha JO - Peptides VL - 117 UR - https://doi.org/10.1016/j.peptides.2019.05.002 DO - 10.1016/j.peptides.2019.05.002 ID - Román2019 ER - TY - JOUR AU - Rachdi, L. AU - Aïello, V. AU - Duvillié, B. AU - Scharfmann, R. PY - 2012 DA - 2012// TI - L-leucine alters pancreatic β-cell differentiation and function via the mTor signaling pathway JO - Diabetes VL - 61 UR - https://doi.org/10.2337/db11-0765 DO - 10.2337/db11-0765 ID - Rachdi2012 ER - TY - JOUR AU - Heinis, M. AU - Soggia, A. AU - Bechetoille, C. AU - Simon, M. T. AU - Peyssonnaux, C. AU - Rustin, P. PY - 2012 DA - 2012// TI - HIF1α and pancreatic β-cell development JO - FASEB J. VL - 26 UR - https://doi.org/10.1096/fj.11-199224 DO - 10.1096/fj.11-199224 ID - Heinis2012 ER - TY - JOUR AU - Pang, Y. AU - Kartsonaki, C. AU - Guo, Y. AU - Bragg, F. AU - Yang, L. AU - Bian, Z. PY - 2017 DA - 2017// TI - Diabetes, plasma glucose and incidence of pancreatic cancer: a prospective study of 0.5 million Chinese adults and a meta-analysis of 22 cohort studies JO - Int J Cancer. VL - 140 UR - https://doi.org/10.1002/ijc.30599 DO - 10.1002/ijc.30599 ID - Pang2017 ER - TY - JOUR AU - Li, W. AU - Liu, H. AU - Qian, W. AU - Cheng, L. AU - Yan, B. AU - Han, L. PY - 2018 DA - 2018// TI - Hyperglycemia aggravates microenvironment hypoxia and promotes the metastatic ability of pancreatic cancer JO - Comput Struct Biotechnol J. VL - 16 UR - https://doi.org/10.1016/j.csbj.2018.10.006 DO - 10.1016/j.csbj.2018.10.006 ID - Li2018 ER - TY - JOUR AU - Carlessi, R. AU - Chen, Y. AU - Rowlands, J. AU - Cruzat, V. F. AU - Keane, K. N. AU - Egan, L. PY - 2017 DA - 2017// TI - GLP-1 receptor signalling promotes β-cell glucose metabolism via mTOR-dependent HIF-1α activation JO - Sci Rep. VL - 7 UR - https://doi.org/10.1038/s41598-017-02838-2 DO - 10.1038/s41598-017-02838-2 ID - Carlessi2017 ER - TY - JOUR AU - Velde, S. AU - Hogan, M. F. AU - Montminy, M. PY - 2011 DA - 2011// TI - mTOR links incretin signaling to HIF induction in pancreatic beta cells JO - Proc Natl Acad Sci USA VL - 108 UR - https://doi.org/10.1073/pnas.1114228108 DO - 10.1073/pnas.1114228108 ID - Velde2011 ER - TY - JOUR AU - Lee, K. E. AU - Spata, M. AU - Maduka, R. AU - Vonderheide, R. H. AU - Simon, M. C. PY - 2018 DA - 2018// TI - Hif1α deletion limits tissue regeneration via aberrant B cell accumulation in experimental pancreatitis JO - Cell Rep. VL - 23 UR - https://doi.org/10.1016/j.celrep.2018.05.071 DO - 10.1016/j.celrep.2018.05.071 ID - Lee2018 ER - TY - JOUR AU - Sankar, K. S. AU - Altamentova, S. M. AU - Rocheleau, J. V. PY - 2019 DA - 2019// TI - Hypoxia induction in cultured pancreatic islets enhances endothelial cell morphology and survival while maintaining beta-cell function JO - PLoS ONE VL - 14 UR - https://doi.org/10.1371/journal.pone.0222424 DO - 10.1371/journal.pone.0222424 ID - Sankar2019 ER - TY - JOUR AU - Jia, X. AU - Sharma, A. AU - Kumagai-Braesch, M. AU - Wernerson, A. M. AU - Sörenby, A. K. AU - Yamamoto, S. PY - 2012 DA - 2012// TI - Exendin-4 increases the expression of hypoxia-inducible factor-1α in rat islets and preserves the endocrine cell volume of both free and macroencapsulated islet grafts JO - Cell Transplant VL - 21 UR - https://doi.org/10.3727/096368911X627408 DO - 10.3727/096368911X627408 ID - Jia2012 ER - TY - JOUR AU - Sun, S. AU - Xia, C. AU - Xu, Y. PY - 2020 DA - 2020// TI - HIF-1α induced lncRNA LINC00511 accelerates the colorectal cancer proliferation through positive feedback loop JO - Biomed Pharmacother Biomed Pharmacother. VL - 125 UR - https://doi.org/10.1016/j.biopha.2020.110014 DO - 10.1016/j.biopha.2020.110014 ID - Sun2020 ER - TY - JOUR AU - Li, X. AU - Deng, S. J. AU - Zhu, S. AU - Jin, Y. AU - Cui, S. P. AU - Chen, J. Y. PY - 2016 DA - 2016// TI - Hypoxia-induced lncRNA-NUTF2P3-001 contributes to tumorigenesis of pancreatic cancer by derepressing the miR-3923/KRAS pathway JO - Oncotarget. VL - 7 UR - https://doi.org/10.18632/oncotarget.6830 DO - 10.18632/oncotarget.6830 ID - Li2016 ER - TY - JOUR AU - Ou, Z. L. AU - Zhang, M. AU - Ji, L. D. AU - Luo, Z. AU - Han, T. AU - Lu, Y. B. PY - 2019 DA - 2019// TI - Long noncoding RNA FEZF1-AS1 predicts poor prognosis and modulates pancreatic cancer cell proliferation and invasion through miR-142/HIF-1alpha and miR-133a/EGFR upon hypoxia/normoxia JO - J Cell Physiol. VL - 234 UR - https://doi.org/10.1002/jcp.28188 DO - 10.1002/jcp.28188 ID - Ou2019 ER - TY - JOUR AU - Liu, M. AU - Zhong, J. AU - Zeng, Z. AU - Huang, K. AU - Ye, Z. AU - Deng, S. PY - 2019 DA - 2019// TI - Hypoxia-induced feedback of HIF-1α and lncRNA-CF129 contributes to pancreatic cancer progression through stabilization of p53 protein JO - Theranostics. VL - 9 UR - https://doi.org/10.7150/thno.30988 DO - 10.7150/thno.30988 ID - Liu2019 ER - TY - JOUR AU - Ganapathy-Kanniappan, S. PY - 2018 DA - 2018// TI - Molecular intricacies of aerobic glycolysis in cancer: current insights into the classic metabolic phenotype JO - Crit Rev Biochem Mol Biol VL - 53 UR - https://doi.org/10.1080/10409238.2018.1556578 DO - 10.1080/10409238.2018.1556578 ID - Ganapathy-Kanniappan2018 ER - TY - JOUR AU - Tirpe, A. A. AU - Gulei, D. AU - Ciortea, S. M. AU - Crivii, C. AU - Berindan-Neagoe, I. PY - 2019 DA - 2019// TI - Hypoxia: overview on hypoxia-mediated mechanisms with a focus on the role of HIF genes JO - Int J Mol Sci. VL - 20 UR - https://doi.org/10.3390/ijms20246140 DO - 10.3390/ijms20246140 ID - Tirpe2019 ER - TY - JOUR AU - Shen, Y. AU - Chen, G. AU - Zhuang, L. AU - Xu, L. AU - Lin, J. AU - Liu, L. PY - 2019 DA - 2019// TI - ARHGAP4 mediates the Warburg effect in pancreatic cancer through the mTOR and HIF-1α signaling pathways JO - Onco Targets Ther. VL - 12 UR - https://doi.org/10.2147/OTT.S207560 DO - 10.2147/OTT.S207560 ID - Shen2019 ER - TY - JOUR AU - Shukla, S. K. AU - Purohit, V. AU - Mehla, K. AU - Gunda, V. AU - Chaika, N. V. AU - Vernucci, E. PY - 2017 DA - 2017// TI - MUC1 and HIF-1alpha signaling crosstalk induces anabolic glucose metabolism to impart gemcitabine resistance to pancreatic cancer JO - Cancer Cell VL - 32 UR - https://doi.org/10.1016/j.ccell.2017.06.004 DO - 10.1016/j.ccell.2017.06.004 ID - Shukla2017 ER - TY - JOUR AU - Chaika, N. V. AU - Gebregiworgis, T. AU - Lewallen, M. E. AU - Purohit, V. AU - Radhakrishnan, P. AU - Liu, X. PY - 2012 DA - 2012// TI - MUC1 mucin stabilizes and activates hypoxia-inducible factor 1 alpha to regulate metabolism in pancreatic cancer JO - Proc Natl Acad Sci USA VL - 109 UR - https://doi.org/10.1073/pnas.1203339109 DO - 10.1073/pnas.1203339109 ID - Chaika2012 ER - TY - JOUR AU - Jiang, Y. AU - Wu, G. H. AU - He, G. D. AU - Zhuang, Q. L. AU - Xi, Q. L. AU - Zhang, B. PY - 2015 DA - 2015// TI - The effect of silencing HIF-1α gene in BxPC-3 cell line on glycolysis-related gene expression, cell growth, invasion, and apoptosis JO - Nutr Cancer VL - 67 UR - https://doi.org/10.1080/01635581.2015.1085584 DO - 10.1080/01635581.2015.1085584 ID - Jiang2015 ER - TY - JOUR AU - He, G. AU - Jiang, Y. AU - Zhang, B. AU - Wu, G. PY - 2014 DA - 2014// TI - The effect of HIF-1α on glucose metabolism, growth and apoptosis of pancreatic cancerous cells JO - Asia Pacific J Clin Nutr. VL - 23 ID - He2014 ER - TY - JOUR AU - Malakar, P. AU - Stein, I. AU - Saragovi, A. AU - Winkler, R. AU - Stern-Ginossar, N. AU - Berger, M. PY - 2019 DA - 2019// TI - Long noncoding RNA MALAT1 regulates cancer glucose metabolism by enhancing mTOR-mediated translation of TCF7L2 JO - Cancer Res VL - 79 UR - https://doi.org/10.1158/0008-5472.CAN-18-1432 DO - 10.1158/0008-5472.CAN-18-1432 ID - Malakar2019 ER - TY - JOUR AU - Xiang, J. AU - Hu, Q. AU - Qin, Y. AU - Ji, S. AU - Xu, W. AU - Liu, W. PY - 2018 DA - 2018// TI - TCF7L2 positively regulates aerobic glycolysis via the EGLN2/HIF-1alpha axis and indicates prognosis in pancreatic cancer JO - Cell Death Dis. VL - 9 UR - https://doi.org/10.1038/s41419-018-0367-6 DO - 10.1038/s41419-018-0367-6 ID - Xiang2018 ER - TY - JOUR AU - Zhang, H. AU - Chen, J. AU - Liu, F. AU - Gao, C. AU - Wang, X. AU - Zhao, T. PY - 2014 DA - 2014// TI - CypA, a gene downstream of HIF-1alpha, promotes the development of PDAC JO - PLoS ONE VL - 9 UR - https://doi.org/10.1371/journal.pone.0092824 DO - 10.1371/journal.pone.0092824 ID - Zhang2014 ER - TY - JOUR AU - Zhao, Q. AU - Chen, S. AU - Zhu, Z. AU - Yu, L. AU - Ren, Y. AU - Jiang, M. PY - 2018 DA - 2018// TI - miR-21 promotes EGF-induced pancreatic cancer cell proliferation by targeting Spry2 JO - Cell Death Dis. VL - 9 UR - https://doi.org/10.1038/s41419-018-1182-9 DO - 10.1038/s41419-018-1182-9 ID - Zhao2018 ER - TY - JOUR AU - Mace, T. A. AU - Collins, A. L. AU - Wojcik, S. E. AU - Croce, C. M. AU - Lesinski, G. B. AU - Bloomston, M. PY - 2013 DA - 2013// TI - Hypoxia induces the overexpression of microRNA-21 in pancreatic cancer cells JO - J Surg Res. VL - 184 UR - https://doi.org/10.1016/j.jss.2013.04.061 DO - 10.1016/j.jss.2013.04.061 ID - Mace2013 ER - TY - JOUR AU - Ito, E. AU - Yana, I. AU - Fujita, C. AU - Irifune, A. AU - Takeda, M. AU - Madachi, A. PY - 2010 DA - 2010// TI - The role of MT2-MMP in cancer progression JO - Biochem Biophys Res Commun VL - 393 UR - https://doi.org/10.1016/j.bbrc.2010.01.105 DO - 10.1016/j.bbrc.2010.01.105 ID - Ito2010 ER - TY - JOUR AU - Zhu, S. AU - Zhou, Y. AU - Wang, L. AU - Zhang, J. AU - Wu, H. AU - Xiong, J. PY - 2011 DA - 2011// TI - Transcriptional upregulation of MT2-MMP in response to hypoxia is promoted by HIF-1alpha in cancer cells JO - Mol Carcinog VL - 50 UR - https://doi.org/10.1002/mc.20678 DO - 10.1002/mc.20678 ID - Zhu2011 ER - TY - JOUR AU - Dai, Z. J. AU - Gao, J. AU - Ma, X. B. AU - Yan, K. AU - Liu, X. X. AU - Kang, H. F. PY - 2012 DA - 2012// TI - Up-regulation of hypoxia inducible factor-1alpha by cobalt chloride correlates with proliferation and apoptosis in PC-2 cells JO - J Exp Clin Cancer Res CR. VL - 31 UR - https://doi.org/10.1186/1756-9966-31-28 DO - 10.1186/1756-9966-31-28 ID - Dai2012 ER - TY - JOUR AU - Zhang, W. AU - Yuan, W. AU - Song, J. AU - Wang, S. AU - Gu, X. PY - 2018 DA - 2018// TI - LncRNA CPS1-IT1 suppresses EMT and metastasis of colorectal cancer by inhibiting hypoxia-induced autophagy through inactivation of HIF-1α JO - Biochimie VL - 144 UR - https://doi.org/10.1016/j.biochi.2017.10.002 DO - 10.1016/j.biochi.2017.10.002 ID - Zhang2018 ER - TY - JOUR AU - Vikram, A. AU - Anish, R. AU - Kumar, A. AU - Tripathi, D. N. AU - Kaundal, R. K. PY - 2017 DA - 2017// TI - Oxidative stress and autophagy in metabolism and longevity JO - Oxid Med Cell Longev. VL - 2017 UR - https://doi.org/10.1155/2017/3451528 DO - 10.1155/2017/3451528 ID - Vikram2017 ER - TY - JOUR AU - Zhu, H. AU - Wang, D. AU - Zhang, L. AU - Xie, X. AU - Wu, Y. AU - Liu, Y. PY - 2014 DA - 2014// TI - Upregulation of autophagy by hypoxia-inducible factor-1alpha promotes EMT and metastatic ability of CD133 + pancreatic cancer stem-like cells during intermittent hypoxia JO - Oncol Rep VL - 32 UR - https://doi.org/10.3892/or.2014.3298 DO - 10.3892/or.2014.3298 ID - Zhu2014 ER - TY - JOUR AU - Li, X. AU - Lee, Y. AU - Kang, Y. AU - Dai, B. AU - Perez, M. R. AU - Pratt, M. PY - 2019 DA - 2019// TI - Hypoxia-induced autophagy of stellate cells inhibits expression and secretion of lumican into microenvironment of pancreatic ductal adenocarcinoma JO - Cell Death Differ VL - 26 UR - https://doi.org/10.1038/s41418-018-0207-3 DO - 10.1038/s41418-018-0207-3 ID - Li2019 ER - TY - JOUR AU - Kourtidis, A. AU - Lu, R. AU - Pence, L. J. AU - Anastasiadis, P. Z. PY - 2017 DA - 2017// TI - A central role for cadherin signaling in cancer JO - Exp Cell Res VL - 358 UR - https://doi.org/10.1016/j.yexcr.2017.04.006 DO - 10.1016/j.yexcr.2017.04.006 ID - Kourtidis2017 ER - TY - JOUR AU - Zhu, S. AU - Deng, S. AU - He, C. AU - Liu, M. AU - Chen, H. AU - Zeng, Z. PY - 2018 DA - 2018// TI - Reciprocal loop of hypoxia-inducible factor-1alpha (HIF-1alpha) and metastasis-associated protein 2 (MTA2) contributes to the progression of pancreatic carcinoma by suppressing E-cadherin transcription JO - J Pathol VL - 245 UR - https://doi.org/10.1002/path.5089 DO - 10.1002/path.5089 ID - Zhu2018 ER - TY - JOUR AU - Chen, S. AU - Chen, J. Z. AU - Zhang, J. Q. AU - Chen, H. X. AU - Yan, M. L. AU - Huang, L. PY - 2016 DA - 2016// TI - Hypoxia induces TWIST-activated epithelial-mesenchymal transition and proliferation of pancreatic cancer cells in vitro and in nude mice JO - Cancer Lett VL - 383 UR - https://doi.org/10.1016/j.canlet.2016.09.027 DO - 10.1016/j.canlet.2016.09.027 ID - Chen2016 ER - TY - JOUR AU - Zhu, G. H. AU - Huang, C. AU - Feng, Z. Z. AU - Lv, X. H. AU - Qiu, Z. J. PY - 2013 DA - 2013// TI - Hypoxia-induced snail expression through transcriptional regulation by HIF-1alpha in pancreatic cancer cells JO - Dig Dis Sci VL - 58 UR - https://doi.org/10.1007/s10620-013-2841-4 DO - 10.1007/s10620-013-2841-4 ID - Zhu2013 ER - TY - JOUR AU - Deng, S. J. AU - Chen, H. Y. AU - Ye, Z. AU - Deng, S. C. AU - Zhu, S. AU - Zeng, Z. PY - 2018 DA - 2018// TI - Hypoxia-induced LncRNA-BX111 promotes metastasis and progression of pancreatic cancer through regulating ZEB1 transcription JO - Oncogene VL - 37 UR - https://doi.org/10.1038/s41388-018-0382-1 DO - 10.1038/s41388-018-0382-1 ID - Deng2018 ER - TY - JOUR AU - Lu, Y. AU - Ji, N. AU - Wei, W. AU - Sun, W. AU - Gong, X. AU - Wang, X. PY - 2017 DA - 2017// TI - MiR-142 modulates human pancreatic cancer proliferation and invasion by targeting hypoxia-inducible factor 1 (HIF-1alpha) in the tumor microenvironments JO - Biol Open. VL - 6 UR - https://doi.org/10.1242/bio.021774 DO - 10.1242/bio.021774 ID - Lu2017 ER - TY - JOUR AU - Li, F. AU - Tan, H. AU - Singh, J. AU - Yang, J. AU - Xia, X. AU - Bao, J. PY - 2013 DA - 2013// TI - A 3D multiscale model of cancer stem cell in tumor development JO - BMC Syst Biol. VL - 7 UR - https://doi.org/10.1186/1752-0509-7-S2-S12 DO - 10.1186/1752-0509-7-S2-S12 ID - Li2013 ER - TY - JOUR AU - Zhou, P. AU - Li, B. AU - Liu, F. AU - Zhang, M. AU - Wang, Q. AU - Liu, Y. PY - 2017 DA - 2017// TI - The epithelial to mesenchymal transition (EMT) and cancer stem cells: implication for treatment resistance in pancreatic cancer JO - Mol Cancer. VL - 16 UR - https://doi.org/10.1186/s12943-017-0624-9 DO - 10.1186/s12943-017-0624-9 ID - Zhou2017 ER - TY - JOUR AU - Hashimoto, O. AU - Shimizu, K. AU - Semba, S. AU - Chiba, S. AU - Ku, Y. AU - Yokozaki, H. PY - 2011 DA - 2011// TI - Hypoxia induces tumor aggressiveness and the expansion of CD133-positive cells in a hypoxia-inducible factor-1α-dependent manner in pancreatic cancer cells JO - Pathobiology VL - 78 UR - https://doi.org/10.1159/000325538 DO - 10.1159/000325538 ID - Hashimoto2011 ER - TY - JOUR AU - Maeda, K. AU - Ding, Q. AU - Yoshimitsu, M. AU - Kuwahata, T. AU - Miyazaki, Y. AU - Tsukasa, K. PY - 2016 DA - 2016// TI - CD133 modulate HIF-1alpha expression under hypoxia in EMT phenotype pancreatic cancer stem-like cells JO - Int J Mol Sci. VL - 17 UR - https://doi.org/10.3390/ijms17071025 DO - 10.3390/ijms17071025 ID - Maeda2016 ER - TY - JOUR AU - Chen, S. AU - Zhang, J. AU - Chen, J. AU - Wang, Y. AU - Zhou, S. AU - Huang, L. PY - 2019 DA - 2019// TI - RER1 enhances carcinogenesis and stemness of pancreatic cancer under hypoxic environment JO - J Exp Clin Cancer Res CR. VL - 38 UR - https://doi.org/10.1186/s13046-018-0986-x DO - 10.1186/s13046-018-0986-x ID - Chen2019 ER - TY - JOUR AU - Zhu, H. AU - Wang, D. AU - Liu, Y. AU - Su, Z. AU - Zhang, L. AU - Chen, F. PY - 2013 DA - 2013// TI - Role of the Hypoxia-inducible factor-1 alpha induced autophagy in the conversion of non-stem pancreatic cancer cells into CD133 + pancreatic cancer stem-like cells JO - Cancer Cell Int VL - 13 UR - https://doi.org/10.1186/1475-2867-13-119 DO - 10.1186/1475-2867-13-119 ID - Zhu2013 ER - TY - JOUR AU - Chiorean, E. G. AU - Coveler, A. L. PY - 2015 DA - 2015// TI - Pancreatic cancer: optimizing treatment options, new, and emerging targeted therapies JO - Drug Design Dev Ther. VL - 9 UR - https://doi.org/10.2147/DDDT.S60328 DO - 10.2147/DDDT.S60328 ID - Chiorean2015 ER - TY - JOUR AU - Wang, F. AU - Xia, X. AU - Yang, C. AU - Shen, J. AU - Mai, J. AU - Kim, H. C. PY - 2018 DA - 2018// TI - SMAD4 gene mutation renders pancreatic cancer resistance to radiotherapy through promotion of autophagy JO - Clin Cancer Res VL - 24 UR - https://doi.org/10.1158/1078-0432.CCR-17-3435 DO - 10.1158/1078-0432.CCR-17-3435 ID - Wang2018 ER - TY - JOUR AU - Chand, S. AU - O’Hayer, K. AU - Blanco, F. F. AU - Winter, J. M. AU - Brody, J. R. PY - 2016 DA - 2016// TI - The landscape of pancreatic cancer therapeutic resistance mechanisms JO - Int J Biol Sci. VL - 12 UR - https://doi.org/10.7150/ijbs.14951 DO - 10.7150/ijbs.14951 ID - Chand2016 ER - TY - JOUR AU - Robey, R. W. AU - Polgar, O. AU - Deeken, J. AU - To, K. W. AU - Bates, S. E. PY - 2007 DA - 2007// TI - ABCG2: determining its relevance in clinical drug resistance JO - Cancer Metastasis Rev. VL - 26 UR - https://doi.org/10.1007/s10555-007-9042-6 DO - 10.1007/s10555-007-9042-6 ID - Robey2007 ER - TY - JOUR AU - He, X. AU - Wang, J. AU - Wei, W. AU - Shi, M. AU - Xin, B. AU - Zhang, T. PY - 2016 DA - 2016// TI - Hypoxia regulates ABCG2 activity through the activation of ERK1/2/HIF-1alpha and contributes to chemoresistance in pancreatic cancer cells JO - Cancer Biol Ther VL - 17 UR - https://doi.org/10.1080/15384047.2016.1139228 DO - 10.1080/15384047.2016.1139228 ID - He2016 ER - TY - JOUR AU - Cheng, Z. X. AU - Wang, D. W. AU - Liu, T. AU - Liu, W. X. AU - Xia, W. B. AU - Xu, J. PY - 2014 DA - 2014// TI - Effects of the HIF-1α and NF-κB loop on epithelial-mesenchymal transition and chemoresistance induced by hypoxia in pancreatic cancer cells JO - Oncol Rep VL - 31 UR - https://doi.org/10.3892/or.2014.3022 DO - 10.3892/or.2014.3022 ID - Cheng2014 ER - TY - JOUR AU - Arora, S. AU - Bhardwaj, A. AU - Singh, S. AU - Srivastava, S. K. AU - McClellan, S. AU - Nirodi, C. S. PY - 2013 DA - 2013// TI - An undesired effect of chemotherapy: gemcitabine promotes pancreatic cancer cell invasiveness through reactive oxygen species-dependent, nuclear factor κB- and hypoxia-inducible factor 1α-mediated up-regulation of CXCR4 JO - J Biol Chem. VL - 288 UR - https://doi.org/10.1074/jbc.M113.484576 DO - 10.1074/jbc.M113.484576 ID - Arora2013 ER - TY - JOUR AU - Luo, G. AU - Xia, X. AU - Wang, X. AU - Zhang, K. AU - Cao, J. AU - Jiang, T. PY - 2018 DA - 2018// TI - miR-301a plays a pivotal role in hypoxia-induced gemcitabine resistance in pancreatic cancer JO - Exp Cell Res VL - 369 UR - https://doi.org/10.1016/j.yexcr.2018.05.013 DO - 10.1016/j.yexcr.2018.05.013 ID - Luo2018 ER - TY - JOUR AU - Zhao, T. AU - Jin, F. AU - Xiao, D. AU - Wang, H. AU - Huang, C. AU - Wang, X. PY - 2020 DA - 2020// TI - IL-37/STAT3/HIF-1α negative feedback signaling drives gemcitabine resistance in pancreatic cancer JO - Theranostics. VL - 10 UR - https://doi.org/10.7150/thno.42416 DO - 10.7150/thno.42416 ID - Zhao2020 ER - TY - JOUR AU - Milanović, D. AU - Firat, E. AU - Grosu, A. L. AU - Niedermann, G. PY - 2013 DA - 2013// TI - Increased radiosensitivity and radiothermosensitivity of human pancreatic MIA PaCa-2 and U251 glioblastoma cell lines treated with the novel Hsp90 inhibitor NVP-HSP990 JO - Radiat Oncol (London, England). VL - 8 UR - https://doi.org/10.1186/1748-717X-8-42 DO - 10.1186/1748-717X-8-42 ID - Milanović2013 ER - TY - JOUR AU - Nagaraju, G. P. AU - Zakka, K. M. AU - Landry, J. C. AU - Shaib, W. L. AU - Lesinski, G. B. AU - El-Rayes, B. F. PY - 2019 DA - 2019// TI - Inhibition of HSP90 overcomes resistance to chemotherapy and radiotherapy in pancreatic cancer JO - Int J Cancer VL - 145 UR - https://doi.org/10.1002/ijc.32227 DO - 10.1002/ijc.32227 ID - Nagaraju2019 ER - TY - JOUR AU - Huang, C. AU - Li, Z. AU - Li, N. AU - Li, Y. AU - Chang, A. AU - Zhao, T. PY - 2018 DA - 2018// TI - Interleukin 35 expression correlates with microvessel density in pancreatic ductal adenocarcinoma, recruits monocytes, and promotes growth and angiogenesis of xenograft tumors in mice JO - Gastroenterology VL - 154 UR - https://doi.org/10.1053/j.gastro.2017.09.039 DO - 10.1053/j.gastro.2017.09.039 ID - Huang2018 ER - TY - JOUR AU - Zhang, W. AU - Xiong, Z. AU - Wei, T. AU - Li, Q. AU - Tan, Y. AU - Ling, L. PY - 2018 DA - 2018// TI - Nuclear factor 90 promotes angiogenesis by regulating HIF-1α/VEGF-A expression through the PI3K/Akt signaling pathway in human cervical cancer JO - Cell Death Dis. VL - 9 UR - https://doi.org/10.1038/s41419-018-0334-2 DO - 10.1038/s41419-018-0334-2 ID - Zhang2018 ER - TY - JOUR AU - Azoitei, N. AU - Becher, A. AU - Steinestel, K. AU - Rouhi, A. AU - Diepold, K. AU - Genze, F. PY - 2016 DA - 2016// TI - PKM2 promotes tumor angiogenesis by regulating HIF-1α through NF-κB activation JO - Mol Cancer. VL - 15 UR - https://doi.org/10.1186/s12943-015-0490-2 DO - 10.1186/s12943-015-0490-2 ID - Azoitei2016 ER - TY - JOUR AU - Nagaraju, G. P. AU - Park, W. AU - Wen, J. AU - Mahaseth, H. AU - Landry, J. AU - Farris, A. B. PY - 2013 DA - 2013// TI - Antiangiogenic effects of ganetespib in colorectal cancer mediated through inhibition of HIF-1α and STAT-3 JO - Angiogenesis VL - 16 UR - https://doi.org/10.1007/s10456-013-9373-6 DO - 10.1007/s10456-013-9373-6 ID - Nagaraju2013 ER - TY - JOUR AU - Lang, S. A. AU - Moser, C. AU - Gaumann, A. AU - Klein, D. AU - Glockzin, G. AU - Popp, F. C. PY - 2007 DA - 2007// TI - Targeting heat shock protein 90 in pancreatic cancer impairs insulin-like growth factor-I receptor signaling, disrupts an interleukin-6/signal-transducer and activator of transcription 3/hypoxia-inducible factor-1alpha autocrine loop, and reduces orthotopic tumor growth JO - Clinical Cancer Res VL - 13 UR - https://doi.org/10.1158/1078-0432.CCR-07-1104 DO - 10.1158/1078-0432.CCR-07-1104 ID - Lang2007 ER - TY - JOUR AU - Liu, Y. AU - Steinestel, K. AU - Rouhi, A. AU - Armacki, M. AU - Diepold, K. AU - Chiosis, G. PY - 2017 DA - 2017// TI - STK33 participates to HSP90-supported angiogenic program in hypoxic tumors by regulating HIF-1alpha/VEGF signaling pathway JO - Oncotarget. VL - 8 UR - https://doi.org/10.18632/oncotarget.20535 DO - 10.18632/oncotarget.20535 ID - Liu2017 ER - TY - JOUR AU - Tung, K. H. AU - Lin, C. W. AU - Kuo, C. C. AU - Li, L. T. AU - Kuo, Y. H. AU - Lin, C. W. PY - 2013 DA - 2013// TI - CHC promotes tumor growth and angiogenesis through regulation of HIF-1alpha and VEGF signaling JO - Cancer Lett VL - 331 UR - https://doi.org/10.1016/j.canlet.2012.12.001 DO - 10.1016/j.canlet.2012.12.001 ID - Tung2013 ER - TY - JOUR AU - Shan, T. AU - Ma, J. AU - Ma, Q. AU - Guo, K. AU - Guo, J. AU - Li, X. PY - 2013 DA - 2013// TI - β2-AR-HIF-1α: a novel regulatory axis for stress-induced pancreatic tumor growth and angiogenesis JO - Curr Mol Med VL - 13 UR - https://doi.org/10.2174/15665240113139990055 DO - 10.2174/15665240113139990055 ID - Shan2013 ER - TY - JOUR AU - Reeves, E. AU - James, E. PY - 2017 DA - 2017// TI - Antigen processing and immune regulation in the response to tumours JO - Immunology VL - 150 UR - https://doi.org/10.1111/imm.12675 DO - 10.1111/imm.12675 ID - Reeves2017 ER - TY - JOUR AU - Andrade, F. L. AU - Tay, R. E. AU - Pan, D. AU - Luoma, A. M. AU - Ito, Y. AU - Badrinath, S. PY - 2018 DA - 2018// TI - Antibody-mediated inhibition of MICA and MICB shedding promotes NK cell-driven tumor immunity JO - Science (New York, NY). VL - 359 UR - https://doi.org/10.1126/science.aao0505 DO - 10.1126/science.aao0505 ID - Andrade2018 ER - TY - JOUR AU - Lu, Y. AU - Hu, J. AU - Sun, W. AU - Duan, X. AU - Chen, X. PY - 2015 DA - 2015// TI - Hypoxia-mediated immune evasion of pancreatic carcinoma cells JO - Mol Med Rep. VL - 11 UR - https://doi.org/10.3892/mmr.2015.3144 DO - 10.3892/mmr.2015.3144 ID - Lu2015 ER - TY - JOUR AU - Ou, Z. L. AU - Luo, Z. AU - Wei, W. AU - Liang, S. AU - Gao, T. L. AU - Lu, Y. B. PY - 2019 DA - 2019// TI - Hypoxia-induced shedding of MICA and HIF1A-mediated immune escape of pancreatic cancer cells from NK cells: role of circ_0000977/miR-153 axis JO - RNA Biol VL - 16 UR - https://doi.org/10.1080/15476286.2019.1649585 DO - 10.1080/15476286.2019.1649585 ID - Ou2019 ER - TY - JOUR AU - Takahashi, K. AU - Ehata, S. AU - Koinuma, D. AU - Morishita, Y. AU - Soda, M. AU - Mano, H. PY - 2018 DA - 2018// TI - Pancreatic tumor microenvironment confers highly malignant properties on pancreatic cancer cells JO - Oncogene VL - 37 UR - https://doi.org/10.1038/s41388-018-0144-0 DO - 10.1038/s41388-018-0144-0 ID - Takahashi2018 ER - TY - JOUR AU - Spivak-Kroizman, T. R. AU - Hostetter, G. AU - Posner, R. AU - Aziz, M. AU - Hu, C. AU - Demeure, M. J. PY - 2013 DA - 2013// TI - Hypoxia triggers hedgehog-mediated tumor-stromal interactions in pancreatic cancer JO - Cancer Res VL - 73 UR - https://doi.org/10.1158/0008-5472.CAN-11-1433 DO - 10.1158/0008-5472.CAN-11-1433 ID - Spivak-Kroizman2013 ER - TY - JOUR AU - Li, N. AU - Li, Y. AU - Li, Z. AU - Huang, C. AU - Yang, Y. AU - Lang, M. PY - 2016 DA - 2016// TI - Hypoxia Inducible Factor 1 (HIF-1) recruits macrophage to activate pancreatic stellate cells in pancreatic ductal adenocarcinoma JO - Int J Mol Sci. VL - 17 UR - https://doi.org/10.3390/ijms17060799 DO - 10.3390/ijms17060799 ID - Li2016 ER - TY - JOUR AU - Katagiri, T. AU - Kobayashi, M. AU - Yoshimura, M. AU - Morinibu, A. AU - Itasaka, S. AU - Hiraoka, M. PY - 2018 DA - 2018// TI - HIF-1 maintains a functional relationship between pancreatic cancer cells and stromal fibroblasts by upregulating expression and secretion of Sonic hedgehog JO - Oncotarget. VL - 9 UR - https://doi.org/10.18632/oncotarget.24156 DO - 10.18632/oncotarget.24156 ID - Katagiri2018 ER - TY - JOUR AU - Cho, I. R. AU - Kaowinn, S. AU - Moon, J. AU - Soh, J. AU - Kang, H. Y. AU - Jung, C. R. PY - 2015 DA - 2015// TI - Oncotropic H-1 parvovirus infection degrades HIF-1alpha protein in human pancreatic cancer cells independently of VHL and RACK1 JO - Int J Oncol VL - 46 UR - https://doi.org/10.3892/ijo.2015.2922 DO - 10.3892/ijo.2015.2922 ID - Cho2015 ER - TY - JOUR AU - Wilkes, J. G. AU - O’Leary, B. R. AU - Du, J. AU - Klinger, A. R. AU - Sibenaller, Z. A. AU - Doskey, C. M. PY - 2018 DA - 2018// TI - Pharmacologic ascorbate (P-AscH(-)) suppresses hypoxia-inducible factor-1alpha (HIF-1alpha) in pancreatic adenocarcinoma JO - Clin Exp Metas VL - 35 UR - https://doi.org/10.1007/s10585-018-9876-z DO - 10.1007/s10585-018-9876-z ID - Wilkes2018 ER - TY - JOUR AU - Sibenaller, Z. A. AU - Welsh, J. L. AU - Du, C. AU - Witmer, J. R. AU - Schrock, H. E. AU - Du, J. PY - 2014 DA - 2014// TI - Extracellular superoxide dismutase suppresses hypoxia-inducible factor-1alpha in pancreatic cancer JO - Free Radical Biol Med VL - 69 UR - https://doi.org/10.1016/j.freeradbiomed.2014.02.002 DO - 10.1016/j.freeradbiomed.2014.02.002 ID - Sibenaller2014 ER - TY - JOUR AU - Chen, H. AU - Guan, Y. AU - Yuan, G. AU - Zhang, Q. AU - Jing, N. PY - 2014 DA - 2014// TI - A perylene derivative regulates HIF-1alpha and Stat3 signaling pathways JO - Bioorg Med Chem VL - 22 UR - https://doi.org/10.1016/j.bmc.2013.10.018 DO - 10.1016/j.bmc.2013.10.018 ID - Chen2014 ER - TY - JOUR AU - Miyake, K. AU - Nishioka, M. AU - Imura, S. AU - Batmunkh, E. AU - Uto, Y. AU - Nagasawa, H. PY - 2012 DA - 2012// TI - The novel hypoxic cytotoxin, TX-2098 has antitumor effect in pancreatic cancer; possible mechanism through inhibiting VEGF and hypoxia inducible factor-1alpha targeted gene expression JO - Exp Cell Res VL - 318 UR - https://doi.org/10.1016/j.yexcr.2012.03.013 DO - 10.1016/j.yexcr.2012.03.013 ID - Miyake2012 ER - TY - JOUR AU - Tang, L. R. AU - Wu, J. X. AU - Cai, S. L. AU - Huang, Y. X. AU - Zhang, X. Q. AU - Fu, W. K. PY - 2018 DA - 2018// TI - Prolyl hydroxylase domain 3 influences the radiotherapy efficacy of pancreatic cancer cells by targeting hypoxia-inducible factor-1α JO - Onco Targets Ther. VL - 11 UR - https://doi.org/10.2147/OTT.S187615 DO - 10.2147/OTT.S187615 ID - Tang2018 ER - TY - JOUR AU - Lv, C. AU - Kong, H. AU - Dong, G. AU - Liu, L. AU - Tong, K. AU - Sun, H. PY - 2014 DA - 2014// TI - Antitumor efficacy of α-solanine against pancreatic cancer in vitro and in vivo JO - PLoS ONE VL - 9 UR - https://doi.org/10.1371/journal.pone.0087868 DO - 10.1371/journal.pone.0087868 ID - Lv2014 ER - TY - JOUR AU - Wen, Z. AU - Huang, C. AU - Xu, Y. AU - Xiao, Y. AU - Tang, L. AU - Dai, J. PY - 2016 DA - 2016// TI - α-Solanine inhibits vascular endothelial growth factor expression by down-regulating the ERK1/2-HIF-1α and STAT3 signaling pathways JO - Eur J Pharmacol VL - 771 UR - https://doi.org/10.1016/j.ejphar.2015.12.020 DO - 10.1016/j.ejphar.2015.12.020 ID - Wen2016 ER - TY - JOUR AU - Seo, J. H. AU - Jung, K. H. AU - Son, M. K. AU - Yan, H. H. AU - Ryu, Y. L. AU - Kim, J. PY - 2013 DA - 2013// TI - Anti-cancer effect of HS-345, a new tropomyosin-related kinase A inhibitor, on human pancreatic cancer JO - Cancer Lett VL - 338 UR - https://doi.org/10.1016/j.canlet.2013.04.002 DO - 10.1016/j.canlet.2013.04.002 ID - Seo2013 ER - TY - JOUR AU - Ryu, Y. L. AU - Jung, K. H. AU - Son, M. K. AU - Yan, H. H. AU - Kim, S. J. AU - Shin, S. PY - 2014 DA - 2014// TI - Anticancer activity of HS-527, a novel inhibitor targeting PI3-kinase in human pancreatic cancer cells JO - Cancer Lett VL - 353 UR - https://doi.org/10.1016/j.canlet.2014.07.001 DO - 10.1016/j.canlet.2014.07.001 ID - Ryu2014 ER - TY - JOUR AU - Nagaraju, G. P. AU - Zhu, S. AU - Ko, J. E. AU - Ashritha, N. AU - Kandimalla, R. AU - Snyder, J. P. PY - 2015 DA - 2015// TI - Antiangiogenic effects of a novel synthetic curcumin analogue in pancreatic cancer JO - Cancer Lett VL - 357 UR - https://doi.org/10.1016/j.canlet.2014.12.007 DO - 10.1016/j.canlet.2014.12.007 ID - Nagaraju2015 ER - TY - JOUR AU - Niu, F. AU - Li, Y. AU - Lai, F. F. AU - Ni, L. AU - Ji, M. AU - Jin, J. PY - 2015 DA - 2015// TI - LB-1 exerts antitumor activity in pancreatic cancer by inhibiting HIF-1alpha and Stat3 signaling JO - J Cell Physiol VL - 230 UR - https://doi.org/10.1002/jcp.24949 DO - 10.1002/jcp.24949 ID - Niu2015 ER - TY - JOUR AU - Zhao, T. AU - Ren, H. AU - Jia, L. AU - Chen, J. AU - Xin, W. AU - Yan, F. PY - 2015 DA - 2015// TI - Inhibition of HIF-1α by PX-478 enhances the anti-tumor effect of gemcitabine by inducing immunogenic cell death in pancreatic ductal adenocarcinoma JO - Oncotarget. VL - 6 UR - https://doi.org/10.18632/oncotarget.2948 DO - 10.18632/oncotarget.2948 ID - Zhao2015 ER - TY - JOUR AU - Schwartz, D. L. AU - Bankson, J. A. AU - Lemos, R. AU - Lai, S. Y. AU - Thittai, A. K. AU - He, Y. PY - 2010 DA - 2010// TI - Radiosensitization and stromal imaging response correlates for the HIF-1 inhibitor PX-478 given with or without chemotherapy in pancreatic cancer JO - Mol Cancer Ther VL - 9 UR - https://doi.org/10.1158/1535-7163.MCT-09-0768 DO - 10.1158/1535-7163.MCT-09-0768 ID - Schwartz2010 ER - TY - JOUR AU - Yasui, H. AU - Matsumoto, S. AU - Devasahayam, N. AU - Munasinghe, J. P. AU - Choudhuri, R. AU - Saito, K. PY - 2010 DA - 2010// TI - Low-field magnetic resonance imaging to visualize chronic and cycling hypoxia in tumor-bearing mice JO - Cancer Res VL - 70 UR - https://doi.org/10.1158/0008-5472.CAN-10-1350 DO - 10.1158/0008-5472.CAN-10-1350 ID - Yasui2010 ER - TY - JOUR AU - Dewhirst, M. W. PY - 2009 DA - 2009// TI - Relationships between cycling hypoxia, HIF-1, angiogenesis and oxidative stress JO - Radiat Res VL - 172 UR - https://doi.org/10.1667/RR1926.1 DO - 10.1667/RR1926.1 ID - Dewhirst2009 ER - TY - JOUR AU - Olbryt, M. AU - Habryka, A. AU - Student, S. AU - Jarząb, M. AU - Tyszkiewicz, T. AU - Lisowska, K. M. PY - 2014 DA - 2014// TI - Global gene expression profiling in three tumor cell lines subjected to experimental cycling and chronic hypoxia JO - PLoS ONE VL - 9 UR - https://doi.org/10.1371/journal.pone.0105104 DO - 10.1371/journal.pone.0105104 ID - Olbryt2014 ER -