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Fig. 3 | Cancer Cell International

Fig. 3

From: Long non-coding RNA NORAD exhaustion represses prostate cancer progression through inhibiting TRIP13 expression via competitively binding to miR-495-3p

Fig. 3

Effects of miR-495-3p mimic on the proliferation, apoptosis, migration, and invasion of PCa cells. a QRT-PCR was conducted for the evaluation of the expression of miR-495-3p in both 22Rv1 and LNCaP cells. a–j 22Rv1 and LNCaP cells were transfected with miR-NC or miR-495-3p. b, c The proliferation capacity of 22Rv1 and LNCaP cells was determined with MTT assay. d The apoptotic rate of 22Rv1 and LNCaP cells was assessed using flow cytometry assay. e, f The migration and invasion capacities of 22Rv1 and LNCaP cells were detected using transwell assay. g–j The levels of Bax, Cleaved-casp-3, and Bcl-2 in 22Rv1 and LNCaP cells were measured by western blot analysis. The experiments were performed in triplicate. ***P < 0.001

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Cancer Cell International

ISSN: 1475-2867

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