Fig. 2From: Cytotoxicity study of the interleukin-12-expressing recombinant Newcastle disease virus strain, rAF-IL12, towards CT26 colon cancer cells in vitro and in vivoMTT assay showing the cytotoxicity activity of AF2240-i and rAF-IL12 against CT26 and 3T3 cells 72 h post-infection. Percentage of viability of two cell lines (CT26 and 3T3) when treated with seven doses of virus treatment (AF2240-i or rAF-IL12) after 72 h. The IC50 value (half-maximal inhibitory concentration, HA unit) for AF2240-i-CT26 = 291 ± 0.67; rAF-IL12-CT26 = 276 ± 0.88; AF2240-3T3 = n.d.; rAF-IL12-3T3 = n.d. Data are presented as mean ± S.E.M from triplicate determinationsBack to article page