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Fig. 4 | Cancer Cell International

Fig. 4

From: Cytotoxicity study of the interleukin-12-expressing recombinant Newcastle disease virus strain, rAF-IL12, towards CT26 colon cancer cells in vitro and in vivo

Fig. 4

Cell cycle analysis of CT2 cells at different cell cycle phase. a Histogram of cell cycle analysis showing distribution of CT26 cells at different cell cycle phase (G0, G1, S, and G2) after 72 h period of treatment with AF2240-i and rAF-IL12. The G0 peak appeared first in the histogram followed by G1, S, and G2 peaks indicating the percentage of cells population in those aforementioned cell cycle phases. Percentage of cells population in each peak was calculated from a total number of 10, 000 cells in each flow cytometry run. b Percentage of cells population at different cell cycle phase analysed by flow cytometer following treatment with AF2240-i (291 HA titre) and rAF-IL12 (276 HA titre) in CT26 cells. Data are presented as mean ± S.E.M from triplicate determinations. Mean values with statistical difference at p < 0.05 between control, AF2240-i, and rAF-IL12 are indicated with *

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